Abstract: Ixodes scapularis and Ixodes pacificus are the two species of blacklegged ticks that act as vectors of transmission of the spirochete bacterium Borrelia burgdorferi to small mammals or human host, which cause Lyme disease in humans, also known as Lyme borreliosis (cdc.gov 2016; Qiu et al. 2002). After the pathogen’s initial entry through the skin, it proliferates in the blood and cerebrospinal fluid; Borrelia burgdorferi has also been seen in much smaller quantities in the following locations: ‘myocardium, retina, muscle, bone, spleen, liver, meninges, and brain’, which is the primary cause of more severe secondary symptoms of untreated infection (cdc.gov 2016; Steere 2004).
What are the requirements for survival and reproduction
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burgdorferi populations in the Mid-West and Northeast share a fairly recent common evolutionary ancestor despite geographic separation. The previous inference is supported by several contributing factors: both tick-borne populations of B. burgdorferi have very little genetic variation due to the minimal number of observed polymorphic sites present in each population, and both populations have similar linked allele combinations. More than likely, the above information suggests small population sizes and a recent common ancestor for both Northeast and Mid-Western populations of B. burgdorferi. However, Brisson et al. also noted that the independent populations have begun to minimally diverge from one another. The small evolutionary divergence between the two populations is not responsible for the higher rate of infection in the Northeast. Host populations in the Northeast encounter a different set of circumstances than hosts in the Mid-Western populations such as: host life-style and environmental factors, including closer proximity and different pathogen reservoirs, causing more frequent host-pathogen interactions, and thus a larger percentage of infected individuals in the Northeast than Mid-West
Two innovations had a tremendous impact on Roman architecture. One was not a Roman invention, although it was improved upon, which was the arch. The other was without a doubt a
Character Analysis Essay In the novel The Boy Who Harnessed the Wind, William and his family live in a small town called Malawi. William is a student, that loves to learn. “...you will always find him in the town's library.” (pg 139 paragraph 2 by William Kamkwamba).
According to Dr. Dietrich Klinghardt (a world renowned Lyme expert), Lyme disease is considered the plague of the century due to the large number of people with chronic Lyme disease and the associated co-infections. The number one symptom of Lyme is chronic fatigue. People can have Lyme for a very long time and not be properly diagnosed because current laboratory testing comes up short with being able to detect it. One of the main reasons for this is because chronic Lyme does not live in the blood but rather in the tissues. It is an intracellular organism meaning it lives inside the cell. Lyme has different shapes: spirochete (like a spring), cyst with a hard shell, and acellular (without an outer cell membrane). Lyme likes to set up a sanctuary in the body such as in the brain, teeth (such as under a root canal or in a cavitation), vertebrae, breast tissue, and lymph nodes. It looks for a place where it can be protected and the body is vulnerable preferably in fatty tissue or under a biofilm. While traditionally Lyme disease is considered a tick-borne disease, recent findings have discovered that it is an insect-borne disease that can get transferred
“Lyme disease got its name from where it was first discovered in Lyme, Connecticut in 1975” (healthychildren.org). “Since then there has been thousands of cases reported of the disease. The ticks live in low and high seasonal temperatures and high humidity” (healthychildren.org). Lyme Disease most common to occur in the Northeast, North-central states, or West Coast. On behalf of the Northeast, I can tell you that ticks are everywhere in this region. They like to live in tall grasses and woody areas. “The small insects more than often latch onto the foot or lower leg and crawl up the body, and travel up the body with a destination of the head. On their normal hosts, ticks also usually crawl up; they want to blood feed around the
Thesis Statement: “According to the Center of Disease Control, Lyme disease is the most commonly reported vector borne illness in the United States”(Lyme Disease: Data and statistics, 2016).
Lyme disease has emerged as the most common vector borne infectious disease in the United States and has presented a growing challenge to public health officials over the past three decades. The infection represents a significant disease burden to the population of the United States with nearly 30,000 new cases diagnosed per year and an estimated additional 270,000 annual incident cases that go unreported. The disease results from a bacterial infection with the spirochete bacteria B. burgdorferi. This bacterial agent is transmitted to humans from the bite of a tick and is most commonly associated Ixodes species blacklegged ticks. These ticks represent the largest genus of the family Ixodidae and mainly inhabit temperate forest or grassland
Rocky Mountain spotted fever (RMSF), also called blue disease [1], was first identified in the rocky mountain region of the United States but has since spread across Northern and Southern America. The disease is transmitted by the bacterium Rickettsia rickettsia and is spread to humans by the Dermacentor tick species. It is a fatal illness in humans but is curable with effective antibiotic treatment of Tetracycline and Chloramphenicol which, since the 1940s has drastically decreased the number of deaths associated with RMSF. Diagnosis of the disease in the early stages is often difficult due to the diverse clinical features, therefore the disease is often referred to as “the great imitator”. Symptoms usually appear with 2-14 days of infection
Lyme borreliosis or Lyme disease can be devastating both physically and mentally for victims. The disease is transmitted by a vector, specifically a tick, which infects their host by biting and infecting them with pathological spirochete bacteria known as Borrelia burgdorferi (Muschart & Blommaert, 2015). There are several species of Borrelia globally, and as a group, the bacteria are referred to as Borrelia burgdorferi sensu lato (Pearson, 2015). The disease originated from, Lyme Connecticut, of which it was named, after a patient was mistakenly diagnosed with rheumatoid arthritis when the cause of their disease was B. burgdorferi or Lyme disease (Snow, 2013). Lyme disease is classified as one of the most common and growing vector-born disease in the United States as well as Europe (Snow, 2013). Understanding how Lyme disease progresses through the body as well as the disease’s signs and symptoms are essential to understanding how to treat the disease and stop it from spreading throughout the body with destructive results. With a disease as potentially devastating as Lyme disease, early treatment is required for a better outcome (Pearson, 2015). This research paper will discuss the pathophysiology of three Lyme conditions known as Lyme arthritis, Lyme neuroborreliosis, and Lyme carditis and provide an overview of the signs and symptoms of Lyme disease and treatments, and how to prevent infection.
The Bubonic Plague or ‘Black Death’ is a highly infectious and potentially fatal disease that spread rapidly throughout Europe in the Middle Ages. The disease carrying Bacterium, Yersinia pestis, caused millions of deaths in the 1300s due to its highly contagious nature. Many people contracted the Bubonic Plague from bacteria carrying fleas, which carried the plague bacteria from an infected rodent (A.D.A.M, 2015). This particular disease isn’t usually spread from person to person, but instead through small rodents and animals that carry infected fleas, many people became infected from flea bites or direct contact with the infected skin or fluids of an animal, (Rare Diseases, 2014) However, according to some credible scientists, it is believed
Borrelia burgdorferi is brought in through the tick bite to the bloodstream. From there, it
The bubonic plague has been around for almost two thousand years. In most early cases the plague was spread from China along the Silk Road. The Silk Road was the over land trade route from the orient that silk, spices, and other trade able goods from the east to western Europe. In most cases rats carrying the Oriental Rat Flea or another animal carrying the flea would move to a new location. Once that animal died the flea would move to another host which could be a human. Once bitten by the flea a bubo begins to form when the bubo begins to ooze fluid the illness can then be passed through touch. As stated above in the Middle
Lyme disease is a tick-borne illness, a disease caused by a bacterium borrelia burgdorferi, borrelia mayonii, borrelia afzelii, and or borrelia garinii. The bacterium borrelia burgdorferi is the causative agent in the United States. There are fifty-two known types of borrelia and twenty-one of those are the lyme disease group. Borrelia is from an infected tick bite by a blacklegged tick. The infection from the bite will enter through the skin through that bite and it will make its way to and through the bloodstream. To get the infection, the tick must be attached to you for thirty-six to forty-eight hours.
Justinian's code is a set of laws that emperor Justinian preserved from the Roman rules and updated and added to them. Many of the laws today are based if of or can be traced back to these rules. The Roman Empire was the Roman laws. These laws were based off of Roman culture.
One of the most common Tick communicable diseases plaguing the United States today is a human transferable infection called Lyme disease, which is spread by Deer Ticks Ixodes scapularis, they are small arthropods often found in wooded areas of eastern United states (Orkin.com “Deer ticks” accessed may 8 2016); transmission of the infection occurs when an contaminated deer tick I. scapularis bites its victim transmitting the blood borne infection to its host; a bacteria called spirochete Borrelia burgdorferi. (CDC) invades the body and begins it journey of destruction. Symptoms are not felt right away, yet over the
Lyme Disease is the number one tick-borne disease in the United States and in Massachusetts. It is considered a vector disease because it is spread through the bite of a black-legged tick (also known as a deer tick) that carries the bacterium, Borrelia burgdorferi. Lyme was first diagnosed in 1975 in Lyme, CT and the bacterium that causes Lyme was discovered in 1982 by Willy Burgdorfer (Todar, 2012, p. 1). Lyme disease spreads rapidly and can impact many different organ systems including the joints, brain, heart, and muscles. Symptoms can lay dormant for months or years or occur quickly after the initial tick bite. Difficulty of diagnosis adds to the burden of Lyme disease in Massachusetts. “Because of its initial presentation as a skin rash, …the difficulty in some cases of even considering Lyme disease given its presentation in the form of other more typical illnesses, …Lyme disease in the 1980s became known as ‘the new Great Imitator’ “ (Lyme Disease, n.d.).