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Biology Personal Statement

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I began my undergraduate education with the aim of pursuing a career as a physician. However, after exposure to laboratory research and the discovery of my passion for teaching, I have now been considering obtaining an MD/PhD. I would like to help patients not only as a compassionate physician but also by conducting research that will open doors to health issues faced by many around the world. My interest in obtaining research experience at UT Southwestern is twofold: it will give me an opportunity to conduct full-time biological research and resolve my interest in pursuing a career as a physician-scientist.
I chose Biology as my major primarily because of my interest in human biology. After taking many Biology courses I have developed a fascination …show more content…

Originally, I planned to clone the 659 gene into pLZ12, a commonly used expression vector; however, this procedure caused a lot of trouble because it required a double digest, and one of the restriction enzymes had low activity. Due to this issue, I proceeded with TA cloning since it does not require a restriction digest. Another issue arose during the transformation of the cloned pGEM vector into DH5α, a common E. coli cloning strain. After many repeated failures in transforming the plasmid into DH5α, I did some research and came to understand that DH5α degrades methylated DNA. Thus I used STBL4, a methylation sensitive strain, instead of DH5α. One thing this experience taught me is to never do something in an experiment because many other people have done it; I should always look into the details of each procedure or reagent I want to use in the experiment during the planning phase in order to minimize time wasted …show more content…

One of the most important lessons I have learned and retained is that the goal of a scientist is to tell a story that clearly outlines the implications of the research findings in a simple manner. In addition, this semester, I am interning as a research associate at Parkland Hospital in order to gain exposure to various research environments. This has given me a unique medical perspective, and I hope to further evaluate my interest in medical/scientific research by immersing myself in research training at UT Southwestern. By carrying out experiments while attending classes I haven’t been able to get a complete research experience, so I would really like to put forth all my effort and work full-time on a research project through the UT Southwestern SURF

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