(ii) Ethics in Gene Therapy
According to Blau and Springer (1995), gene therapy is a newly rising approach at the end of the 20th century and aims to open new door for the treatment of various human diseases based on transfer of genetic materials to cells. The recent gene therapy research has focused on treating individuals by targeting the therapy to body cells such as bone marrow or blood cells. This type of gene therapy is not inherited and thus it cannot be passed down on to a person’s children in the future. Meanwhile, gene therapy could also be targeted to egg and sperm cells (knowns as germline gene therapy) which would allow the inserted gene to be passed on to the progeny. Germline gene therapy allows the correction of disease-causing
Genetic Modification is often perceived as the answer to humanity’s faults because it will enhance human abilities, prevent the survival of incapacitating disabilities, and guide the innovation of the future. Sounds pretty good, right? That is not the reality. Genetic modification is not the solution to the ubiquitous problems of the human race, but rather infringes on individual rights, decreases diversity, permits too much power to the human race, and contributes to overpopulation.
DNA are like legos, they work together to build the traits of living things. They are the building blocks of the body. Many scientists today have been figuring out different ways to manipulate, change, add, and subtract genes from the DNA in living things; this is process is called genetic engineering. Some of the living things being experimented on are live people, plants, and animals. Today scientists are debating on the morals of genetic engineering due to what the community thinks of it, because of the christian 's viewpoint of genetic engineering. To some christians it may pose a threat to their, but to others it may be a blessing or a gift. Genetic Engineering is a growing breakthrough in the science community. “Over the last 30 years, the field of genetic engineering has developed rapidly due to the greater understanding of deoxyribonucleic acid (DNA) as the chemical double helix code from which genes are made. The term genetic engineering is used to describe the process by which the genetic makeup of an organism can be altered using “recombinant DNA technology.” This involves the use of laboratory tools to insert, alter, or cut out pieces of DNA that contain one or more genes of interest.”(Pocket K No. 17) Scientist have yet to unlock the full potential of genetic engineering, but the information and the use they have found for it today has reached farther than anyone 's expectations.
Embryonic stem cell research can be easily defined. A stem is defined as something that is developed from. A cell is defined as a microscopic living organism. According to Dennis Hollinger, "Embryonic stem cell research uses from the embryo's inner cell mass that give rise to each of the human body's many different tissue types"(1). In our modern day society, stem cell research has become a controversial topic. Several people strongly oppose the idea of the research, but many are struggling for the continuance of the program. Embryonic stem cell research should be allowed to continue because it aids in the search of cures for diseases, offers an alternative to discarding unused embryos from in vitro fertilization, and is supported by the
Gene therapy is an experimental technique that is used to prevent disease. For future reference, this technique may treat disorders. It may add or remove genes to get rid of a genetic disorder. Gene therapy is a heavily debated subject. There are very respectful points on both sides of this debated topic. The pro side believes that gene therapy is the best thing that is happening to our society. However, opposers of gene therapy believe that people should refrain from proceeding with this biological advancement and it is ethnically incorrect.
With the world of technology making advances so quickly we sometimes forget our own limits as a mortal species. Genetic therapy has the potential to save millions of people from genetic mutations and protein deficiencies. This paper will go on to argue that the Utilitarianism approach in ethics shows all the right things about genetic therapy. The first-time gene therapy was used on a patient dates back in the 1990s when a four-year-old girl had adenosine deaminase deficiency. With this disease, her white blood cells were not doing their job and left her prone to infections. Through the power of genetic therapy some of her white blood cells were extracted, altered to produce adenosine deaminase, and reinjected. This treatment not only saved her life from dangerous diseases but also began a world of opportunities in the medical field. The ethical issue is, is it right or wrong to have that much power to alter genes and to what degree you should be able to modify them. Should people live out their futures the ways they are born or should they live life to the fullest and get the genetic treatments?
whereas they do not have control over other countries governed laws. Allowing the United States to fall behind other countries technical and medical enhancements is not a wise decision. The United States would be taking a drastic step backwards by not saving lives, like this technology has done before(Farahany). Scientists have finally found a safer form of genetic modification and are not being allowed to perform these procedures because of safety regulations that no one can improve without funding to understand what exactly is the problem with this technology.
If you were able to pick what characteristics your child is going to have, would you? From the color of their hair, to maybe even their sexuality. Is it okay to alter the characteristics of your child based on your own opinion of who you want them to be? What about the question of a baby being required to have a genetic screening before or right after birth? Should that be allowed to happen with the fact of the parents, or anyone for that matter, not knowing who is going to have access to these records? In a scientific manner, this seems like it is not that big of a deal. Thinking about this ethically is the what everyone is concerned about. I do not think that this is ethically okay. Where do we draw the line?
In 1990 the first gene therapy procedure gained approval and a four-year-old girl with SCIDs disease was finally able to fight off a simple cold. She is now able to live a normal life with the help of continued treatment of gene therapy. Although gene therapy is an innovative and ideally favorable procedure when it comes to treating diseases, cancer, or inherited disorders, it is still a delicate procedure and is continuously studied to insure it is not only effective but also and most importantly safe. In order to insure the safety of patients a gene therapy drug must get the approval of the FDA before becoming available, as every drug must do. Since gene therapy is still very experimental; there are only a few gene therapy drugs that have been approved by the FDA to treat patients. However, on August 30th, 2017 history was made when the FDA approved Kymriah, the first CAR-T cell therapy drug to be available in the United States. Kymriah is a one-time treatment for patients with B-cell acute lymphoblastic leukemia, it was developed through the research collaboration of Novartis and the University of Pennsylvania, and it is manufactured for each individual patient. Kymriah’s only drawback would be the price tag of $475,000 for a course of treatment, however Novartis plans to wave the fee for patients where Kymriah is not successful.
In other words, they are worried that parents having the ability to control what their child will be like will disrupt the plan that God has created for them. Some also believe that it is unethical to make a decision that will affect a person without their consent, which is exactly what genetic modification would be doing. By changing the plan that God has created and making a decision on behalf of a person without their consent are both seen as unethical and going against religious
DNA stands for Deoxyribonucleic acid. Deoxyribonucleic corrosive is an atom that conveys a large portion of the hereditary guidelines utilized as a part of the improvement, working and propagation of all known living creatures and numerous infections. The National Institutes of Health and Welcome Trust from the London UK and Craig Vendor of Celera Genomics from Maryland USA at the same time exhibited the grouping of human DNA in June of 2000, finishing the first significant attempt of the Human Genome Project (HGP) (Ridley 2). As researchers connection human attributes to qualities fragments of DNA found on one or a greater amount of the 23 human
The ethics and human gene patenting are often controversial. The ethical interests of big corporations which are frankly looking to making money and what the common man perceive is completely different which makes this topic disputed about and triggers people. There is a huge concern about the disparities in influence and wealth amongst individuals and concerns about the lack of pellucidity, accountability and public symposium encompassing noteable changes in people’s rights, opportunities and status. Hence, ethical matters are not easily dispersed and need to be thought harder about the essence and justification of patent law itself.
1.Preface : Gene therapy, looks all previous fields of cruel edge scientific report, and was the subject of major ethical debate. Gene therapy has generated could be argued further discussion of other medical discoveries in its infancy because of its ability to influence the human genome. There are two types of gene therapy is currently under discussion, gene therapy and somatic cell gene therapy from germ cells. 2. Point of view for gene therapy research:
If a treatment is implicated before the child is born – germline gene therapy – he or she could lose all trace of that defective gene, and therefore wouldn’t pass the disease on to future generations. In somatic gene therapy, treatment is conducted when the patient is an
Genetic engineering has become increasingly normalized in today’s society, and people are exposed to this technology now more than ever before. Most people are aware that food companies practice genetic engineering on their plants in order to design the most profitable crops, but it isn’t generally known that this same technology can be applied to humans. The concept of picking certain traits and characteristics of a human may appear desirable, but many risks and potential side effects may follow considering that it is unknown what genetic engineering could affect in future generations. Francis Fukuyama, an accomplished and distinguished professor of political economy and philosopher, conveys his concern that genetic engineering is developing at a surprisingly rapid rate. Within his book, Our Posthuman Future: Consequences of the Biotechnology Revolution, he claims that genetic engineering not only will potentially be detrimental for the human race, but due to the change in nature of human beings, such engineering will also result in significantly impacting government and politics. Although genetic engineering can be seen as a huge technological advancement that could potentially help millions, there are drastic negative effects and reasons for disapproving genetic engineering that are too important to be overlooked.
Genetic engineering has to do with manipulating organisms and DNA to create body characteristics. The practice of genetic DNA has shown an increasing amount over the past years. The process of genetic enhancement involves manipulating organisms by using biotechnologies. The technique is by removing a DNA from one life form and transferring it to another set of traits or organism. Certain barriers are conquered, and the procedure involves changing a form of cells, resulting from an improvement or developed organism. GMO which is a (Genetic Modified Organisms) is the operation done in a laboratory where DNA genetic from one particular species or animals is directly forced into another gene from an unrelated subject of plants or even animals.