Systemic Lupus Erythematosus, usually called as SLE or Lupus, is a type of incurable autoimmune disease which affects the hematologic, dermatologic, renal organ system and musculoskeletal. In other words, it attacks mostly the connective tissues of the body. Generally, an autoimmune disease happens when the immune system attacks healthy tissues of the body by producing protein called autoantibodies. This will cause inflammation and damage to the tissues. Inflammation causes indication of injuries such as redness, swelling and pain. The etiology of SLE is still unknown to the world. There is, however, increasing evidence that the presence and accumulation of apoptotic cells play a role in autoimmunity (White, S., and Rosen, A., 2003).
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Let alone the cause of this horrible disease. One of the most commonly suspected reasons for systemic lupus erythemotosus (SLE) is a very low iron count. Low iron has a veriaty of effects on the body including the feeling of being cold, low blood count (anemia), and impaired immune defiecency, ect.. Thus the low iron syptom seems to add up with lupus making doctor think that low iron can have a leading from in the disease.
Systemic lupus erythematosus (SLE) also referred to lupus dates back to the middle ages and has made an explosion in the past 60 years. Even though more than 1.5 million Americans have lupus and 90% of lupus sufferers are women, between the ages of 15 to 44 (Lupus Research Institute), there is little awareness about the disease. 72% of Americans aged 18-34 have either not heard of the disease or know nothing about it (Medical News Today). However, researchers continue on working to have a better understanding of SLE factors, pathophysiology, current treatment and new prospects for treatment.
Lupus is a chronic inflammatory disease of unknown cause that can affect virtually any part of the body. The medical term for Lupus is Systemic Lupus Erythematosus or better known as SLE. With Lupus there is a malfunction in some of the cells of the immune system. "In Lupus, the body overreacts to an unknown stimulus and makes to many antibodies, or proteins directed against body tissue. Thus, Lupus is called an autoimmune disease. ”#
It is not rare for individuals with lupus to undergo muscle throbs and discomfort or have inflammation of certain muscle groups, which causes faintness and loss of intensity. More than 90 percent of people with lupus will encounter joint and/or muscle pain at some time during the path of their illness. In lupus, the immune system of the body raids its own cells and tissues. Precisely, the joints, skin, kidneys, lungs, heart, nervous system, and other organs of the body are affected. Lupus affects generally 10 times as many women as men. Most often, lupus develops in people 18 to 45 years old. (Lahita) Though lupus is most dominant among women, it also may affect men and children, as well as individuals of all ages. Lupus effects each person
Lupus is an autoimmune disease where your own immune system attacks not only pathogens, but your own healthy tissue. It is one of the more severe autoimmune diseases and can seriously impair the life of the sufferer if left untreated, possibly leading to death.
Lupus is a condition that few people know about. Based on the results of a survey from the Lupus Foundation of America, around 72% of Americans aged 18-34 have either not heard of the disease or know nothing about it other than the name, despite this age group being at greatest risk for the condition. Lupus gained more attention from the public in 2015 after singer Selena Gomez announced she had been diagnosed with the condition in her late teens and underwent treatment for the disease. Lupus is a well-known autoimmune disorder disease. Which means that the body's immune system is not functioning normal and it's attacking the normal tissue, instead of the bacteria and viruses or in other words the body's immune system is hurting itself. The
Systemic lupus erythematosus (SLE) is a disease in which a person’s own immune system begins to recognize its own tissues and organs as foreign antigens which causes it to attack and injure those targeted structures (Perspectives 14). Discoid lupus erythematosus (DLE) causes coin-shaped lesions to appear on the skin and does not affect any other system other than the integumentary (Perspectives 23). As stated on the Mayo Clinic website the etiology of the disease is idiopathic, but it is believed that environmental factors and inherited genetic code may contribute to the formation of lupus. Lupus can also be triggered by sunlight, infections, and medications such as anti-seizure and hypertension prescriptions (Mayo Clinic). Iatrogenic cases of the disease often have their symptoms reduced or eradicated after stopping those medications (Mayo Clinic). Diagnosis of the disease is based upon criteria set in place by the American College of Rheumatology as lupus often affects the muscle and joints (Lupus.org). The list is comprised of eleven common signs and symptoms that have been observed by rheumatologists. They are: Malar or
The American College of Rheumatology (ACR) and the Georgia Council on Lupus Education and Awareness (GCLEA) partnered to increase community awareness on Systemic Lupus Erythematosus (SLE) and to further educate lupus patients throughout the underserved region of southwest Georgia. Systemic Lupus Erythematosus, the most common form of lupus, is an autoimmune disease that causes the immune system to attack needed body tissues (“Lupus,” 2018). This specific type of lupus affects major functions of the body including the brain, lungs, skin, and kidneys. Lupus is commonly difficult to diagnose in humans due to its vague symptoms that mimic the symptoms of other major conditions (‘Lupus,” 2017). Presently, researchers are unaware of the origins
Lupus is an autoimmune disease that attacks women between the ages of 15 and 40. It occurs less often in men than in women. The people affected by lupus vary depending on the country or region. In the US alone, the prevalence rate is highest among Asians of Hawaii, blacks of Caribbean origin, and Native Americans of the Sioux, Arapahoe, and Crow tribes. Lupus is a disease that affects the immune system. We can think of the immune system as an army within the body with hundreds of defenders (known as antibodies). They defend the body from attack by germs and viruses. In lupus, however, the immune system becomes overactive and creates antibodies that attack healthy tissues in the body, such as: the skin, kidneys, lungs, heart and brain.
The cause of Lupus is still an enigma, and this is one chronic condition that still can’t be easily defined.
Makover, M. & Zieve, D. (2011, February 14). Systemic Lupus Erythematosus. National Center for Biotechnology Information. Retrieved July
What is lupus? “Lupus is a chronic, autoimmune disease that can damage any part of the body (Lupus).” An autoimmune disease can be extremely detrimental to the body. This disease occurs when the body creates an antibody that goes against substances naturally present in the body. When your body is against itself, you have nothing to help heal your body and nourish it back to health, making treatment and recovery harder. As an eight-year-old child, I didn’t notice that my mother had lupus until it was too late. After her death in 2007 I began to notice all of the signs that I missed at first and started reflecting on my whole life and memories. All those signs those were clear as day and I missed all of them. Lupus can be caused by a numerous
Systemic Lupus Erythematosus is a chronic autoimmune disease which causes inflammation of your joints, tissues, and organs. The inflammation presents itself as heat, pain, swelling and redness. SLE is a variable disease that doesn’t take any one particular course; therefore its unpredictability makes it even more devastating. No two people will experience the same disease symptoms or severity level. As S.L.E progresses there will be periods of very subtle to no symptoms at all called remission or an exacerbation of symptoms called flares.
Systemic lupus erythematosus, or simply lupus is a chronic autoimmune disease or immune system malfunction. A person's immune system normally protects the person from viruses, bacteria and other foreign materials. When a person has an autoimmune diseases like lupus, the immune system turns against itself and attacks itself.
Lupus is a potentially life threatening disease that effects about 1.5 million Americans. Lupus can effect many different parts of the body. Lupus is a type of autoimmune system disorder in which the body cannot distinguish the difference between foreign antibodies and its own organs. So basically what happens is that the body ends up attacking its own organs thinking they are foreign substances. (The Lupus Foundation of America)