Acute renal failure, also known as acute kidney injury is described to be a rapid loss of
kidney function, or a rapid decline in renal filtration function. The first signs of acute renal
failure can be found by a rise in serum creatinine concentration or azotemia, which is a rise
in blood urea nitrogen (BUN) concentration. Symptoms of acute renal failure may include,
little or no urine when urinating, swelling in the legs and feet, not feeling like eating,
nausea and vomiting, feeling confused, restless, sleepy or anxious, or pain in the back
below the rib cage.
The pathophysiology of acute renal failure is still uncertain though it is thought to be
caused by tubular necrosis and vasoconstriction.
…show more content…
The third cause is the
postrenal, which is when there are obstructions in the urinary tract. This one affects the
normal flow of urine out of both kidneys from a blockage caused by kidney stones, a tumor,
an injury or from an enlarged prostate gland.
The diagnostic exams used to diagnose acute renal failure are the blood urea nitrogen
(BUN), the creatinine clearance, the serum creatinine, the serum potassium and the
urinalysis. Other tests to diagnose renal failure can include, an ultrasound to reveal any
obstruction to the kidneys, an imaging test which include CT scans or MRI to reveal a more
detailed image of the kidneys and other organs, a kidney biopsy where a small piece of
tissue can be removed and examined, or an x-ray to examine for pulmonary edema, fluid
retention in the lungs.
The first stage of renal failure is the acute renal failure stage, which is the crucial stage.
The patient must pay close attention to signs and symptoms in this stage. Signs may
include drowsiness, headache, and back pain, typically on the side also referred to as flank
pain. The second stage is the chronic renal failure, which is accompanied by feelings of
physical weakness, loss of appetite, generalized swelling and shortness of breath. The third
stage is end stage renal
Intrarenal acute renal failure- accounts for 30% to 40% of the cases of ARF- generally results from acute tubular necrosis due to disturbances within the glomerulus or renal tubules. ATN most often occurs after surgery but is also associated with sepsis, severe trauma, including severe burns,
This is sudden injury to the kidneys which stops them working instantly or nearly instantly, AKI can range from the kidneys only to stop functioning slightly or to completely stop working. Due to the name of it some people think that it is physical injury or blow to the kidneys however it is a result in complications of other conditions. It is usually seen in older people who are very unwell and get admitted to hospital, it’s vital that AKI is detected quickly as if AKI
All the symptoms that were described were based on the kidney functions, so more and further
Chronic Kidney Disease (CKD) is a disease that is described as a loss of kidney function gradually over time. As kidney function decreases, the waste collection in the body’s blood becomes high and makes the individual feel sick. This disease can lead to other complications in the body such as anemia, poor nutritional health, high blood pressure, and nerve damage. These complications will begin to progress and show as CKD progresses to advanced stages. Early detection of this disease is essential when it comes to treatment. If CKD is diagnosed early enough the disease progression can be slowed down and managed. This disease will eventually lead to failure of the kidneys
Injury to the glomerulus and the tubules presents the onset of Intra-renal failure (Matzke, 2011). Some of the frequent causes for Intra-renal failure are glomerulonephritis; pyelonephritis; and tubular injury. Post-renal failure develops from things like ureteroliths, tumors, or anatomic impediments. Opposite of the acute form, the chronic form has a slow onset that has no early stage symptoms. It is important to know that following an acute episode a chronic renal episode often follows, and at this juncture the damage is irreversible. Glomerulonephritis and pyelonephritis combined, has been reported to be the forerunner in as much as half the cases from acute to chronic renal failure. Diabetes mellitus, renal vascular disease, such as atherosclerosis, hypertension, polycystic kidney disease, drug damage, and nephrolith are all examples of other causes of CKD (Pradeep, 2014). Biopsies of kidneys that suffered with CKD reveal smaller kidneys with scarring on the tubules.
In patients with heart failure, hypovolemia, cirrhosis, nephrotic syndrome, or hypoalbuminemia, renal function may be further compromised. BUN, creatinine clearance, and urine output should be monitored closely (Lexi-Comp, 2016).
Lily was a 65 year old lady with stage 5 CKD, she had recently begun hemodialysis treatment three times a week as an inpatient and had been responding well to treatment. During dialysis treatment on the morning of the first day, Lily’s observations showed that she was: tachycardic, hypotensive, tachypnoeaic, had an oxygen saturation level of 88% and was becoming confused and drowsy. It became apparent that Lily had become hypovolaemic. The hypovolaemic shock seen in this patient was of a particular critical nature due to the fact that her dialysis treatment had moved her rapidly through the first two stages of shock with her compensatory mechanisms failing very quickly (Tait, 2012). It was also much harder to identify the early signs of
I agree with you, These 2 terms present the pattern of the beginning and ending of kidney functional impairment. Azotemia is suspected at finding elevated blood urea nitrogen (BUN) which indirectly suggested intake of exogenous nitrogen - protein, and appears at the time of insufficient or dysfunctional filtering of blood... , & uremia occurs at the end of renal damage for which dialysis is needed.
Chronic kidney disease (CKD) is an irreversible condition that progresses causing kidney dysfunction and then to kidney failure. It is classified by a GFR of <60mL/min for longer than 3 months. There are five stages of CKD: Stage 1 has kidney damage but has a GFR ≥ 90. Stage 2 has mild damage and a GFR of 60-89. Stage 3 has moderate damage and a GFR of 30-59. Stage 4 has severe damage and a GFR of 15-29. Stage 5 is also known as end stage renal disease (ESRD), this is kidney failure with a GFR of ≤ 15 and theses patients are typically on dialysis or in need of an immediate transplant. The leading cause of CKD is diabetes. Hypertension is also a major cause. Since most DM patients have HTN,
Nephrotoxins, acute interstitial nephritis, glomerular damage, and vascular damage also correlate with intrarenal acute renal failure (Singh, Levy, & Pusey, 2013). Postrenal acute renal failure is usually a result of a urinary tract obstruction that affects the kidneys bilaterally, which causes the intraluminal pressure upstream from the site of the obstruction to increase with a progressive decrease in the glomerular filtration rate (McCance, Huether, Brashers, & Rote, 2014). A pattern consisting of several hours of anuria with flank pain followed by polyuria is typically found in individuals with postrenal acute renal failure (McCance, Huether, Brashers, & Rote, 2014).
Chronic Kidney Disease (CKD) is among the leading causes of mortality throughout the world, and its prevalence and the health care costs resulting from it are considerable and increasing. CKD commonly is silent and asymptomatic until its late stages. Accordingly, CKD is diagnosed prior to symptomatic stage of kidney failure, resulting in delays in proper interventions and the emergence of adverse consequences in the CKD patients
Acute kidney injury (AKI) is a common clinical issue but the understanding of the syndrome has been re-evaluated, standardised and aprimorated in the past years. The change from acute renal failure to AKI happened due the fact the even mild change in function or structure of the kidney can cause abrupt clinical manifestations such as change in extracellular volume and electrolytes balance and inability to properly excrete nitrogenous waste products like urea. The old terminology is used now saved for cases were renal replacement therapy is been considered due to severity. The AKI diagnostic criteria is based in a 48 hour creatinin serum level rise by 0.3mg/dL or 1.5 times the patient baseline level or urine decrease to a volume less than
High blood pressure which is called hypertension is another common disease which can cause chronic renal failure. This
Imagine that one of your loved ones are in the hospital… they’re very sick and you don’t know what is wrong. The doctor comes in and tells you that your loved one is having kidney failure
There are different types of renal failure such as chronic kidney disease which is a slow progression over time and it can go unnoticed for a long time. Acute renal failure occurs suddenly, happening within a few hours or a few days, if not caught in time