Actinomycosis is a rare, chronic, and slowly progressive granulomatous disease caused by filamentous Gram positive anaerobic bacteria from the Actinomycetaceae family. Actinomyces israelii is the most common etiologic organism of actinomycosis [1]. Less common species include A naeslundii, A odontolyticus, A viscosus, A meyeri, A turicensis, and A radingae [9.10]. Actinomyces are commensals of the humanoropharynx, gastrointestinal tract and urogenital tract. When tissue integrity is breached through a mucosal lesion they can incade local structures and organs and become pathogenic. Actinomycosis is therefore mainly an endogenous infection [9]. The incidence of actinomycosis infection is rare. In the 1970s the incidence in Cleveland, USA, was reported to be one per 300 000, compared with Germany and the Netherlands in the 1960s where it was estimated to be one per million [11]. The Department of Health in the United Kingdom reported that 0.0006% of hospital consultations (71 in total) were for actinomycosis in England between 2002 and 2003[12]. In recent, abdominopelvic actinomycosis of 23 patients for 15 years and 22 patients for 7 years were reported in respective single center in Korea [13-14]. In present study, we reported 13 patients of abdominoplevic actinomycosis for 20 years. Actinomycosis is classified into distinct clinical forms according to the anatomical site infected: orocervicofacial, thoracic, abdominopelvic, central nervous system, musculoskeletal, and disseminated. …show more content…
In present study, all patients had no recurrence after treatment during follow period. The previously reported mortality range is from 0% to 28%. Effect factor of mortality is depending on the site of infection, the time to diagnosis, the time to the start of appropriate treatment, co-existing central nervous system disease [27]. In present study, there was no surgery related complication and
Bacteria are ubiquitous; they can be found on the skin, in the soil, and inside the body. Because of the very nature of this ubiquity, it is important to be able to determine between different strains of bacteria. An example of this is determining the causative agent for a disease so that the patient will be treated with the appropriate antibiotics. It may be important to determine the bacteria in a certain region, because like with enteric bacteria, it is normal to find them in the digestive tract as they are in a symbiotic relationship with our bodies in this area; however, they also cause opportunistic infections in places outside of the digestive tract to our detriment, such as with a urinary tract infection. Some strains of bacteria are common to nosocomial infections, and identifying these bacteria as such helps create the guidelines for healthcare workers in antiseptic technique. All of the morphology and characteristics of each strain of bacteria help us to better understand the role of bacteria in the body as well as helps us understand how they can cause illness, and what treatment regimen to set in place. In lab this semester, a sample of unknown
This particular bacterium is not one that inhabits a specific geographical region as it colonizes within the human body. The disease is
As the flowchart shows, a series of tests were conducted to identify the unknown bacterium #65. Microscopic observation of the gram stain indicated a gram-positive coccus bacterium. S. epidermidis was used as the gram-positive control while E. coli was used as the gram-negative control. This observation led to the elimination of all gram negative and rod-shaped genera: Enterobacter, Citrobacter, Klebsiella, Escherichia, Pseudomonas, Serratia, Alcaligenes, Neisseria, Proteus, Salmonella, Shigella, Erwinia, Veillonella, Flavobacterium, Bacillus, Arthrobacter, Lactobacillus, Listeria and Kurthia (2). By performing the catalase test, it was determined that the bacterium was catalase negative and it did not produce bubbles. M. luteus and E. faecalis were used as positive and negative controls, respectively.
ncluded 1011 patients seen over a fifteen-year period. The patients were checked at short intervals until remission occurred, and these checks were discontinued only when normal function was restored or after a period of one year. For 85 percent of patients the first signs of remission were observed within three weeks after the outbreak; for the last 15 percent remission occurred three to six months later. Seventy-one percent recovered normal mimical function of the face, 13 percent had insignificant sequelae, and the last 16
He reports no major changes in his condition, since his last visit. His pain is rated as 3-6/10, described as dull, hard, aching or worse. Pain is increased with sitting, standing, walking, lifting, looking up and down, turning to the sides, bending, and twisting. He is unable to work. He is very limited physically. He has to modify or avoid social and recreational activities to manage the pain. He feels like his quality of life is severely affected. His pain is 80% in the neck and 20% in the upper extremities, mostly on the
Recurrence rate was 1.9% (12 patients), in which all patient were retreated conservatively and had complete healing, none required surgical intervention.
Per the IME report dated 04/07/14 by Dr.Sharma, MMI has been reached. There is no need for further neurologic treatment, diagnostic testing, follow-up or PT.
Different microbes can transmit and produce different types of diseases and infections. Having an unknown bacterium in the body can be a life and death situation. It is very important especially in the healthcare industry that providers are able to differentiate between organisms that are pathogenic and administer the appropriate treatment to their patients. Applying methods that were previously studied in lab, students must be able to isolate an unknown specimen by using laboratory techniques and biochemical tests.
If there is a tumor present in the patient, it will be surgically removed (if possible, depending on location). If surgical resection is not possible, chemotherapy and/or radiation will be used to target the tumor. Steroid use has been determined as effective, however, some children become steroid dependent and symptoms may reoccur once treatment has been completed. The treatment with the best-documented outcomes is referred to as FLAIR therapy, which is a three-agent protocol involving front-loading high dosages of ACTH (Adrenocorticotropin), IVIG (Intravenous Immunoglobulin), and Rituximab (monoclonal antibody). Early and sufficient immunotherapy is vital for treatment. The goal for any treatment regarding OMS is complete neurological remission (Pranzetelli, 2015).
Several of the healthcare facilities have continued to participate in a long-term follow up study funded by the CDC to collect information about how patients were treated and how they are doing long term. Most patients have done well with treatment and experience few to no issues related to their fungal infection. Increased pain around the injection site and a difficulty thinking and speaking has been reported by a very small number of patients and this could be related to their treatments or their infections. The CDC has gotten reports of eight relapses as of June, 2015, the rate of relapse is 1% of the 753 total cases. A patients infection is considered cured when their symptoms improve and their laboratory test return to normal. Patients magnetic resonance imaging (MRI) have shown abnormalities after the infection has been considered resolved and these should be discussed with their healthcare provider in the context of their overall
disease and Alzheimer’s. Severe infection that has spread to the brain, epilepsy, stroke, and the late
Like most microscopic organisms, gonococcus develops well in warm, clammy situations. It flourishes in the mucous film tissues of the urethra, genitals, throat, and rear-end. It is transmitted through any sort of unprotected penile-vaginal, oral-genital, oral-butt-centric, and genital-butt-centric contact with a contaminated person. Hence, any sexually dynamic individual is in danger of contracting gonorrhea. The microorganisms can be spread even without entrance or discharge. Newborn
Recurrence rate is very low in patients treated at Shouldice Hospital (0.8%) when compared with other hospitals (10%) which results in patients preferring Shouldice Hospital.
This disease causes deafness, brain abscess, meningitis, and if left untreated, death. Surgical removal of infected bone and tissue is, without exception, the exclusive treatment course. Profound deafness is certain since removal of the ossicular chain, the three small bones in the middle ear which convey sound vibrations to the brain, occurs during this surgery. Future reconstructive surgery is possible providing the child remains free of regrowth for at least six
This document will provide in-depth research on the treatment and prevention of Lyme disease. Lyme disease is explained by The Centers for Disease Control and Prevention (2015) as being “caused by the bacterium Borrelia burgdorferi and is transmitted to humans through the bite of infected blacklegged ticks” (What is bacteria? Section, para. 1). As explained, Lyme disease is spread through vector-borne transmissions. A vector-borne transmission is the spread of certain disease due to the bite of a vector. The vector in the case of Lyme disease is the blacklegged tick. Lyme’s etiology is explained by Perez and Bush (2014) as being “recognized in 1976 because of close clustering of cases in Lyme, Connecticut and is now the most commonly reported tick-borne illness in the US” (pg. 1). It is important to understand where a disease comes from so you can know where you are more likely to contract the disease.