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Acid Concentration

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Does the amount of active ingredient in different types of tablets decrease or increase per milligram after its expiration date? Overtime, the concentration of acid in a low dose aspirin tablet increases, as the concentration of acid in a high dose aspirin tablet decreases. However, due to various experimental errors, the claim is not a strong and compelling one. What is assumed to have happened is that both low dose aspirin tablets and high dose aspirin tablets increase in concentration of acid as the expiration is surpassed.
Four different tablets (two new and two expired): Bayer High Dose 325 mg (exp unknown), Bayer High Dose 325 mg (exp 8/18), Bayer Low Dose 81 mg Enteric (exp 4/11), and Bayer Low Dose 81 mg Enteric (exp 8/18) undergo the …show more content…

However, stoichiometry provides a more accurate way of measuring acid concentration, giving specific values in grams and milligrams of acid. The balanced equation ensures that there is a 1:1 ratio between acetylsalicylic acid and sodium hydroxide (Figure 1). By using a 1:1 mole ratio, mL of NaOH can be converted to grams of acetylsalicylic acid per tablet. Therefore, a low dose new tablet using 5mL of NaOH contains 0.09 grams or 90 milligrams of acid (Figure 2). This process is then applied to the other tablets; below lists the results of C9H8O4 per tablet in grams and milligrams (Table …show more content…

Firstly, the Bayer High Dose 325 mg tablets used as an “old and expired tablet” is unidentified in expiration date, but the container seems to look very old. This means that it is uncertain whether the tablets labeled as “old” are actually expired or not (Table 1, 2, and 3). Secondly, not all of the powdered tablet is put into the beaker. Some remain on the papers while others fly out onto the table. Because not all contents are present during the titration process, this could very well affect the calculations measuring the mass of acid per

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