Abnormal Thermoregulation Study

Hypothyroidism can affect the body temperature because it slows down the metabolism. This causes the energy produced to be less. With that

4. Vasodilation peripheral vasodilation increases heat loss by diverting the pre-warmed blood to the surface of the body. Occurs under autonomic stimulation of the hypothalamus. (depends on surrounding temperature – if surrounding air or water is not cooler than skin, the effect is minimal to nonexistent)

Malignant Hyperthermia (MH) is a genetically inherited, pharmacogenic disorder involving a severe malfunction within the skeletal muscles, causing them to be stuck in a contracted state. It is found to be triggered in susceptible patients by the administration of certain anesthetic agents during and after surgical procedures. It may also be activated by the use of other drugs, such as muscle relaxants and triggered by other circumstances such as stress, trauma, and even exercising. Not only are the muscles normal physiology affected, but abnormalities of the whole body occur disrupting its natural homeostasis. If it is not treated immediately, it can be fatal. Susceptibility is found in patients who have had a known family history of MH. In order for a medical professional or a patient to be prepared to handle MH one must understand how it affects the normal physiology of the body, what signs to look for, and how it can be diagnosed, treated, and prevented. There is no cure for MH, but there are specific drugs and precautionary measures that are used to prevent and treat it when a patient is susceptible.

Therapeutic hypothermia, also called targeted temperature management, is a procedure that lowers the body's temperature in order to treat a heart that has suddenly stopped working (cardiac arrest). This procedure is used in emergency situations. During cardiac arrest, the brain cannot get enough oxygen. The brain also starts to swell, which can damage or kill brain cells. Therapeutic hypothermia helps reduce swelling in the brain. It also slows down the body's metabolism and allows the heart and brain to recover.

Malignant Hyperthermia is primarily thought to be an autosomal dominant genetic disorder that causes a hypermetabolic state after administration of volatile anesthetics. When a patient is under anesthesia, the muscles are usually relaxed, but when a patient is experiencing Malignant Hyperthermia crisis, certain IV anesthesia causes the opposite effect. Most inhaled anesthetics other than nitrous oxide, cause or trigger Malignant Hyperthermia. More specifically, the anesthetic agents: Halothane, Chloroform, and Succinylcholine. The genic condition of Malignant Hyperthermia only becomes apparent when a patient is exposed to certain anesthetics such as halothane, which causes muscle rigidity.

My reticuloendothelial system defends me too diligently. We are one of those riding out the biological purification process, our bodies feel that feel more like superheated tin men that’s freezing all at once. If I were to light up my wrenched joints, the constellation of stars and lights would glow on the map, lit up to follow whirling storm fronts . A friend and I trade texts: My fan’s on full blast—I’m not warm enough, I have now wrapped myself in my bed sheet. You?

Sweating starts- The widening of the blood vessels is not enough to let all the heat out and preventing

Malignant hypertension is an inherited condition. It occurs when the patient has a severe reaction caused by being exposed to certain drugs used as a part of the anesthesia for surgical procedures. It can be fatal if it is not treated quickly. In most cases, there are no signs or symptoms until the reaction occurs.

Hot flashes are one of the many side effects of cancer treatment. A hot flash is defined as “a subjective sensation of heat that is associated with objective signs of cutaneous vasodilation and a subsequent drop in core temperature” (Kaplan, Mahon, Cope, Keating, Hill & Jacobson, 2011). Another description of a hot flash is a “sudden sensation of intense warmth that begins in the chest region and rises to the neck and face” (Loprinzi, Barton & Rhodes, 2001). Hot flashes are difficult to measure because they are a subjective experience. Electronic monitoring devices have been used to assess skin temperature and objectively measure hot flashes (Carpenter, 2005). Hot flashes cause discomfort and can affect a patient’s quality of life, especially when associated with night sweats, sleep disruption, and mood swings (Loprinzi, Barton & Rhodes, 2001).

Hypothermia can be prevented by maintaining a neutral thermal environment and reducing heat loss. For prevention in reduction of heat consider the four ways by which the neonate experiences heat loss and intervene appropriately.

Shivering is a common problem during spinal anesthesia. It is the hypothermia that actually lowers the threshold for shivering which induces tachycardia, hypertension, and increase oxygen consumption by 400–500%. [1] In spinal anesthesia, there is peripheral redistribution of heat, loss of vasoconstriction below the level of the block with increase of heat loss from body surfaces, and altered thermoregulation with decrease in shivering thresholds. [2]

Hyperhydrosis is the medical term given to the condition commonly referred to as excessive sweating. It is necessary for our bodies to sweat, and the Sympathetic Nervous System is in charge of this secretion. However, one out of every one hundred people suffers from the hyper-activity of this specific nervous system and is said to have the miserable condition known as hyperhydrosis. Hyperhydrosis can be found in the palms of the hands (palmar hyperhydrosis is the most prevalent of all types) (http://abcnews.go.com/sections/living/dailynews/sweat2020.html), on the bottom of the feet, on the face, on the trunk, and in the armpits where the axillary glands are located. As for a cause, it is not yet known why the nerve stimulation is greater than average in some people (people with hyperhydrosis). However, in Richard G. Glogau, MD’s study he refers to “an unusual hybrid sweat gland with both eccrine and apocrine elements…which is found in patients with axillary hyperhydrosis, and which is capable of a secretory rate of 10-fold higher than normal eccrine glands,” (1998, p.817). It is a horrible condition that causes much embarrassment (sweating through and ruining clothes and not being able to lift arms) and much discomfort. For example, a man named Brandon Burg suffered from hyperhydrosis and would sweat through his shirt in fifteen minutes. He confesses, “I had to wear Kotex under my arms. That was the last straw.”

Without these sensory neurons, people with CIPA cannot feel any pain or temperature. They also lose the nerves by their sweat glands, which leads to anhidrosis – lessened or no sweating. The purpose

As humans when we feel tired or worn out we tend to yawn believing that by doing so it sends oxygen to our bloodstream keeping us awake. Sorry to tell you, but that's a myth. Well what could be the reason why we yawn? To cool down our brains. Psychology professor Andrew Gallup says “When we stretch our jaws, we increase the rate of blood flow to the skull, and as we inhale at the same time, the air changes the temperature of that blood flow, bringing cooler blood to the brains.”

CIVD and blood flow. According to Daanen’s literature review, “[c]old-induced vasodilation (CIVD) in the fingertips generally occurs 5-10 min after the start of local cold exposure of the extremities.” However, Gregson et al found that no difference in femoral artery conductance 30 minutes after immersion of healthy patients’ lower limbs in cold water for 10 minutes. (Buy Daanen. Why the discrepancy?)