Study Guide for Campbell Biology
Study Guide for Campbell Biology
11th Edition
ISBN: 9780134443775
Author: Lisa A. Urry, Michael L. Cain, Steven A. Wasserman, Peter V. Minorsky, Jane B. Reece, Martha R. Taylor, Michael A. Pollock
Publisher: PEARSON
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Chapter 15, Problem 1IQ

Complete the following summary of Morgan’s crosses involving the mutant white-eyed fly by filling in the Punnett square and indicating the genotypes and phenotypes of the F2 generation. (Xw stands for the mutant recessive white allele; Xw+ for the wild-type red allele.) The Y reminds you that this eye color gene is not present on the Y chromosome.

Chapter 15, Problem 1IQ, Complete the following summary of Morgans crosses involving the mutant white-eyed fly by filling in

Genotypes

_____ _____ _____ _____

Phenotypes

_____ _____ _____ _____

Expert Solution & Answer
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Summary Introduction

To complete: The summary of Morgan’s cross that involves the mutant white-eyed fly by filling in the Punnett square and by indicating the genotypes and phenotypes of the F2 generation.

Introduction: Sex chromosomes are those chromosomes that play a crucial role in determination of sex of the individual. They have important function in the development of sexual characteristics in the organisms.

Answer to Problem 1IQ

Pictorial representation: Fig.1 represents the summary of Morgan’s cross that involves the mutant white-eyed fly by filling in the Punnett square and by indicating the genotypes and phenotypes of the F2 generation.

Study Guide for Campbell Biology, Chapter 15, Problem 1IQ

Fig.1: Morgan’s cross of mutant white-eyed fly with the genotypes and phenotypes of the F2 generation

Explanation of Solution

The X and Y chromosomes act as sex chromosomes in most of the organisms. The genes that are present on the sex chromosome are called sex-linked genes. There are approximately 1,100 X-linked genes. On the other hand, Y chromosome contains relatively very few genes.

The sex-linked genes display a unique pattern of inheritance. The expression of recessive X-linked trait requires two copies of alleles in females (homozygous) and only one copy of the allele in males (hemizygous). The probability of a male to receive a single mutated X-linked gene from their mother is high as compared to a female receiving both the X-linked mutated genes from the mother (carrier) and father (carrier).

When Morgan crossed red-eyed female (wild-type) with white-eyed male (mutant), all the offspring were red-eyed in the first generation (F1). Then, he again crossed the F1red-eyed female to the red-eyed male of F1. The typical ratio of 3:1 (red-eyed flies: white eyed flies) was observed in the F2 generation, but all white-eyed flies were males.

Morgan concluded that this could be due to hemizygous condition (presence of single X-chromosome “XW+Y”) of the males. Females required both the mutated alleles to express the phenotype (white eye color), while males needed only one mutated allele to show the phenotype. The probability to inherit both mutated copies is less.

Hence, four genotypes of F2 generation are as follows:

  • XW+XW+
  • XW+XW
  • XW+Y
  • XWY

The four phenotypes of F2 generation are as follows:

  • Red-eyed female
  • Red-eyed female
  • Red-eyed male
  • White-eyed male.

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Suppose gene B is X-linked and is embryonically lethal when homozygous or hemizygous recessive. A man marries a woman who is heterozygous for this gene. They want to have three kids – one girl and two boys. Using a Punnett square, answer the following: What is the probability that they will have a son that dies before birth? _______________________ What is the probability that they will have a daughter who has the same genotype as her mother? _________________ One of their daughters eventually has a child with a man. One of their sons dies before birth. What was the genotype of this daughter? _______________________________     please show me how to get the answer and explain how you got and use a punnet square
A mother is heterozygous for the X-linked gene for colorblindness and also heterozygous for the autosomal inherited sickle cell anemia. She is married to a man who can see color normally and who is heterozygous for sickle cell trait. Using b (colorblind), B (normal color), S (normal hemoglobin), s (sickle cell), answer the following: a. What are the genotypes of the parents? b: What is the probability of having a child who is both color blind and has sickle cell anemia?
The mother of a family with 10 children has blood typeRh+. She also has a very rare condition (elliptocytosis,phenotype E) that causes red blood cells to be oval rather than round in shape but that produces no adverseclinical effects. The father is Rh− (lacks the Rh+ antigen)and has normal red blood cells (phenotype e). The children are 1 Rh+ e, 4 Rh+ E, and 5 Rh− e. Information isavailable on the mother’s parents, who are Rh+ E andRh− e. One of the 10 children (who is Rh+ E) marriessomeone who is Rh+ e, and they have an Rh+ E child.a. Draw the pedigree of this whole family.b. Is the pedigree in agreement with the hypothesisthat the Rh+ allele is dominant and Rh− is recessive?c. What is the mechanism of transmission ofelliptocytosis?d. Could the genes governing the E and Rh phenotypesbe on the same chromosome? If so, estimate the mapdistance between them, and comment on your result
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