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(a) What is the dosage form of the two above drugs?
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(b) What is the administration method for the two above drugs?
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Molnupiravir has not been approved but has been authorized for emergency use by the FDA under an EUA to treat mild to moderate COVID-19 infection. Briefly explain this decision made by FDA based on the knowledge of clinical trials.
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Both drugs are not allowed to be prescribed to person under 18 years old due to insufficient clinical data. Why is it necessary to separately conduct clinical trials for a
younger age group?
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- 1) COVID-19 a. Should there be clinical trails performed by agents (institutions) outside the very drug companies that manufacture them? b. Which factors influence the form of treatment in any given nation (example, amount of moeny, profits to be made, accessibility of the treatment, etc.) c. Which type od approaches you think may work the best in form of minimizing COVID-19 infections and the resulting side effectsA 42 YO adult male weighing 142lb, wo is being treated for HSE (herpes simplex enceplhalitis), has been prescribed acyclovir 10mg/kg/dose IV q 8h for 14days. Acyclovir for injection is available in 10 and 20 mL vials containing 50mg/mL. a) How many mg will the patient receive each day? b) How many mg will the patient receive each dose? c) How many mL will the patient receive each dose? d) How many mL will the patient receive each day?Imagine you are designing a new candidate molecule that can be used as an anti-viral drug to treat SARS-CoV-2. List the basic steps you need to take from the idea to the market.
- A 53 YO adult male weighing 168lb, who is being treated for VZV encephalitis, has been prescribed acycloivr 10mg/kg/dose IV q 8h for 10 days. Acyclovir for injection is availble in 10 and 20 mL vials containing 50mg/mL. a) How many mg will the patient receive each day? b) How many mg will the patient receive each dose? c). How many mL will the patient receive each dose?In caring for a patient receiving therapy -ith a myelosuppressive antineoplastic drug, the nurse notes an order to begin filgrastim after the chemotherapy is completed. Which statement correctly describes -hen the nurse -ill begin the filgrastim therapy? a) It can be started during the chemotherapy.b) It -ill begin immediately after the chemotherapy is completed.c) It -ill be initiated 24 hours after the chemotherapy is completed.d) It -ill not be started until at least 72 hours after the chemotherapy is completed.What are the available dosage forms of:16. Feosol®17. Fluimucil®18. Fosamax®19. Garamycin®20. Imuran®
- I) Describe how the pharmacodynamic (PD) characteristics of different drugs administered concomitantly may lead to additive, synergistic, or antagonistic effects. List specific drug interactions that can occur in the management of HIV patients. II)4. A physician orders Humulin R 35 units qam and q5pm and Humulin N 60 units qam. a) How many 10-mL vials of Humulin R U-100 insulin are needed for a one month supply? b) How many 10-mL vials of Humulin N U-100 insulin are needed for a one month supply?Which of the following statements is true of antiviral drugs? Multiple Choice Famciclovir (Famvir) is an analog of acyclovir that is rapidly converted to acyclovir in the tissues. Valacyclovir (Valtrex) is converted to the active antiviral penciclovir. Acyclovir is designated FDA Pregnancy Category D. Acyclovir is used to treat infections of Herpes that occur after a bone marrow transplant.
- (c) Molnupiravir has not been approved but has been authorized for emergency use by the FDA under an EUA to treat mild to moderate COVID-19 infection. Briefly explain this decision made by FDA based on the knowledge of clinical trials. (d) Both drugs are not allowed to be prescribed to person under 18 years old due to insufficient clinical data. Why is it necessary to separately conduct clinical trials for a younger age group?What are the available dosage forms of:21. Inoflox®22. Isoket®23. Isoxilan®24. Kefox®25. Purinase®1. Why are the drugs given to the patient? Give the drug mechanism of action in relation to the case given to patient Tiktok Pakyaw 2) Give TWO (2) nursing considerations in each medication a) Amiodarone 200 mg b) Mannitol 150 ml c) Citicoline 500mg d) Dulcolax 30 cc e) Alteplase IV r-tpa