The electrons flow from the electron-rich atom of the nucleophile to the electron-poor atom of the alkyl halide. Highlight the electron-poor atom in the alkyl halide. :0:
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- Nucleophilic carbon atoms are often important in the formation of carbon–carbon bonds. Carbon atoms are not good nucleophiles if they do not possess a lone pair of electrons.The compound below can be prepared with an alkyl iodide and a suitable nucleophile. Identify the alkyl iodide and the nucleophile that you would use. For an anionic nucleophile, you do not need to draw the counterion. Alkyl iodide: OH Draw Your Solution Nucleophile: Draw Your Solution SUPPORTWhich is/are NOT TRUE about bimolecular nucleophilic substitution reactions? Select one or more: 1. A carbocation intermediate is formed. 2. A strong nucleophile displaces a halogen atom in a concerted mechanism. 3. Presence of polar aprotic solvents promotes this reaction. 4. Methyl halides react faster than secondary alkyl halides.
- Why is benzene a weak nucleophile?Does doubling the concentration of an alkylhalide and maintaining the alkoxide concentration double the reaction rate? What if the alkylhalide concentration is maintained and the alkoxide concentration is doubled?What is the product of the reaction of bromoethane with each of the following nucleophiles?
- Explain why quinuclidine is a much more reactive nucleophile than triethylamine, even though both compounds have N atoms surrounded by three R groups.What product is formed when 1-bromopropane reacts with each of the following nucleophiles?Explain why pentane-2,4-dione forms two alkylation products (A and B) when the number ofequivalents of base is increased from one to two.
- Explain why a nucleophilic reagent such as ethoxide adds to an alkyne more easily than it adds to an alkeneIdentify the appropriate nucleophile and alkyl halide substrate to prepare this ether: Structure of the alkyl halide substrate? Structure of the nucleophile?Explain why pentane-2,4-dione forms two different alkylation products (A or B) when the number of equivalents of base is increased from one to two.