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- Determine the mechanism of nucleophilic substitution of each reaction and draw the products, including stereochemistr CH₂CH3 CI Br + CN d. + CH3COOH a. acetone + -OCH3 e. DMF f. b. C. ||||| a ||||| Br H Br CH2CH2CH3 + CH3OH DMSO H CH3 CI Br + OCH₂CH3 + CH3CH₂OH5. Using curved arrows please give the mechanism of this reaction, including any regioselectivity or stereoselectivity. P. HBr } DCM BrShow Transcribed Text H₂, Pd/C, EtOH MeMgBr (excès) puis H3O+ Me₂CuLi, Et₂O puis H₂O+ Please draw the mechanism step by step ? ? ?
- 9. Complete Reactions. Provide only the major product for E2&SN2 reactions. E1/SN1 provide all possible products. NaOH Br provide mechanism CI Provide mechanism + CI NaOCH 3 KCN3) Explain how and why the reaction below results in the observed regiochemistryand/or stereochemistry.2. a. b. d. C. oFor each reaction, draw the product(s) and circle the mechanism(s). Include "major be and “minor" when necessary. Stereochemistry must be included for stereoselective reaction "No reaction" is a possible answer. Br Br ts Br CI ta ха но Br CH3ONa CH₂OH KSH acetone Br₂ hv CH3OH NaCN DMSO ser nongaholds zid) no baard E2 E1 SN1 SN2 X. E2 E1 SN1 SN2 X. E2 E1 SN1 SN2 X. E2 E1 SN1 SN2 X• E2 E1 SN1 SN2 X• E2 E1 SN1 SN2 X.
- Consider the nucleophilic substitution reaction shown here. Based on the stereochemistry, does it proceed by an Sy1 or Sy2 mechanism? Explain. OH KOCH3 Enantiomer CH;OH `OCH36. Determine whether each reaction occurs by an SN2, SN1, E1, and/or E2 reaction. Provide a detailed mechanism with curved arrows and the major product(s). CI NaSH DMF OMs NaOH H20, heat LDA Br DMF NaOH H20, heat OH HBr OH H*, H20 heat6. A synthesis of a molecule being explored as an antidepressant drug (J. Org. Chem 2012) utilized the synthetic step shown below. Propose a plausible mechanism for this transformation. AICI3 H,C=CH, Br Br
- Q7. Propose a detail mechanism for the following reaction. Use curved arrow to show the electron movement. H2SO4 он heatA. B. C. D. E. Br Br H H OH Which of these syntheticQ3. Please provide a curved arrow mechanism that can explain the reaction shown below. i) LDA ii) aq. workup Me Me TBSO CI Q4. a) Identify the main products of the following cycloaddition reactions. In each case, provide a curved arrow mechanism that accounts for their formation. Me OH H Me b) Provide a clear drawing that explains the stereochemistry of the product.