Oncologists (cancer doctors) frequently measure the mitotic index of tumor cells when they are removed via surgery or biopsy. What do you think is the value of finding out the mitotic index of these cells?
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- Oncologists (cancer doctors) frequently measure the mitotic index of tumor cells when they are removed via surgery or biopsy. What do you think is the value of finding out the mitotic index of these cells?
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- Describe the role of cell division in at least one of the following areas of biology: Stem cell research Cell cloning for organ replacement therapies Cancer (see the DNA LC’s video on tumor growth for a hint: https://dnalc.cshl.edu/resources/3d/31-tumor-growth.html)In your own words, explain metastasis and why this process is important in the prognosis of a patient, and is this an easy and efficient process for cancer cells, why or why not?What does cancer drugs play in interrupting mitosis of cancer cells? How do these drugs do that?
- Briefly explain what goes wrong with mitosis in the case of cancer cells? How does it spread throughout the body? (metastasis)Which is true for cancer cells: 1) Cell death occurs after a determined number of cell divisions 2) Contact with other cells reduces chance of cell division 3) Cell division occurs in the presence of stop signals.Which of the following traits are common to many cancer cells (more than one answer may be correct)A. Uncontrolled growth and divisionB. Chromosomes abnormalitiesC. Absence of a cytoskeletonD. Decreased adhesion to other cells
- The current way to gauge the effectiveness of chemotherapy is to track the size of the tumor. If the tumor shrinks, the chemotherapy is said to be "working." If cancer stem cells really do act the way we think they do, what will be the new way that the effectiveness of chemotherapy will be evaluated?Tumor growth rate is dependent on which of the following factors? A. B. C. D. Quantity of actively dividing cells Type of malignancy Staging at time of diagnosis Mitotic phase of the cell cycleWhat is the relationship between the cell cycle and cancer production?
- A researcher is studying the effects of a novel cancer drug on cell division and comparing the new drug to a traditional chemotherapy drug. The traditional drug causes numerous side effects such as nausea, vomiting, hair loss and susceptibility to infections due to low white blood cell counts. The novel drug is a targeted therapy (specifically targets the abnormal protein in the cancer cell) and is likely to reduce side effects that patients experience when treated with traditional chemotherapy. One group of cancer patients was treated with the novel drug and a second group of cancer patients was treated with the traditional chemotherapy drug. Prior and subsequent to treatment, a mitotic index was obtained from a tumor sample from each patient as well as a bone marrow sample (bone marrow cells give rise to all blood cell types including red blood cells and white blood cells). Since this is a double-blind study (neither the patient nor the researcher knows which patients received which…Lord Voldemort seeks immortality to rule over the wizarding and muggle world forever. As his loyal servant, you point out to him that in his quest for horcruxes, he has forgotten about the importance of avoiding cancer as he ages. Specifically, which of the following magical spells should he learn to use? A spell that… decreases DNA repair accuracy during mitosis makes him smaller (e.g., fewer total cells) Increase the rate of mitosis increases his number of copies of p53 all of the above none of the aboveHow does the dysregulation of cell cycle checkpoints contribute to the development of cancer?