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In an aldol condensation reaction, what is the difference if we use an ethanolic or aqueous NaOH solution?
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- Differentiate between Aldol and Claisen condensation reaction.In the aldol reaction, why is it important to dissolve both ketones before the catalyst is added?Draw the aldol product for the reaction of the aldehyde shown with NaOH. Assume the reaction is run under conditions that allow the reaction to stop before dehydration. NaOH
- Which statement describes why aldol reactions with ketones are low yielding? A.Ketones do not have acidic protons. B.Ketones are too electron poor at the carbonyl carbon. C.Ketones can attack other ketones well but perform poorly in self-condensations. D.The product of a ketone addition to a ketone has considerable steric strain.All are true or false a) The initially formed b-hydroxy carbonyl compound loses water in a Aldol condensation. b) Equilibrium favors the starting materials with both aldehydes and ketones for Aldol reactions. c)The Claisen reaction is a type of nucleophilic addition? d) The b-hydroxy carbonyl product of an Aldol reaction is oftentimes not the final isolated product. e)b-Ketoester and an enolate are the two starting materials for a Robinson annulationhow might you synthesize the following compound using an aldol reaction? draw the structure of the starting aldehyde(s) or ketone(s) you would use Concepts (References) How might you synthesize the following compound using an aldol reaction? Draw the structure of the starting aldehyde(s) or ketone(s) you would use. сно Concepts Reforences How might you synthesize the following compound using an aldol reaction? Draw the structure of the starti CHO • You do not have to consider stereochemistry. • You do not have to explicitly draw H atoms. • Do not include lone pairs in your answer. They will not be considered in the grading. • Draw one structure per sketcher. Add additional sketchers using the drop-down menu in the bottom t Separate multiple reactants using the + sign from the drop-down menu. P. opy sta