Identify the term that refers to a drug that is very similar to natural chemicals in a normal biochemical reaction in cells but different enough to interfere with the normal division and functions of cells. Multiple Choice Neutropenia Immunosuppressed Antimetabolite Nucleoside
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Identify the term that refers to a drug that is very similar to natural chemicals in a normal biochemical reaction in cells but different enough to interfere with the normal division and functions of cells.
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- A patient has a blood bank history of being type A positive. The patient has recently been diagnosed with carcinoma of the colon and now the reagent anti-B is showing a 1+ reaction with the patient's cells. Other typing results are as expected. Please explain.Cold allodynia is a common side effect of platinum-based chemotherapy drugs. Define this term.Explain what a lysogen is.
- True/False: Neutrophils regulate the production of active cathelicidins (a class of antimicrobial peptides) by segregating the inactive propeptide from the processing enzyme that cleaves and activates it in two different types of cytoplasmic granules. These two types of granules are induced to fuse with phagosomes after ingestion of microbes, bringing the processing enzyme and the propeptide together.List all the possible modes of entry of the drug to the target cell membranes.Discuss how drug hypersensitivity reactions can affect various organs. Include in your answer specific examples and address the underlying mechanisms. Need authentic and correct answer „,, copied , wrong answer gives you multiple downvotes
- CHOICES: Isoniazid Rifampicin Ethambutol None of the Choices Causes more adverse effects to slow acetylators Causes optic neuritis Causes orange secretions Inhibits transcription process in mycobacteria Binds to bacterial DNA gyrase & topoisomeraseA 3-year-old girl was admitted with a diagnosis of acute lymphocytic leukemia. After admission, she was treated by administration of packed red cells, 2 units of platelets, IV fluids, and allopurinol. On the second hospital day, chemotherapy was begun, using IV vincristine and prednisone and intrathecal injections of methotrexate, prednisone, and cytosine arabinoside. She was discharged for home care 5 days later. She was continued on prednisone and allopurinol at home. She received additional chemotherapy 1 month later (11/1) and again on 11/14. On 12/6, she was readmitted because she had painful sores in her mouth and was unable to eat. LABORATORY RESULTS 10/1 10/2 10/3 10/4 11/14 12/6 6/20 Urea N 12.0 4.0 ** ** 15 ** 2.0 (mg/dL) Creatinine 0.7 (mg/dL) 0.7 ** ** ** 1.0 0.7 Uric acid (mg/dL) 12.0 9.2 4.0 1.9 2.3 ** 3.1 WBC 56,300 3,700 ** ** 2,800 3,700 ** (mm³) **indicates test not performed Questions: 1. How would you explain the significant elevations of uric acid on admission? 2.…Discuss the clinical uses of tumor markers in a maximum of 5 sentences.
- identify the different cells in the blood smear image by their phenotypes and state their primary function in the table belowWhat is not true regarding drug delivery uptake? Most nanoparticles enter cells through endocytosis Cells are not able to internalize particles of nanoscale Nanoparticles can be used to deliver high drug doses to cell Nanoparticles can enter the cell via phagocytosis What is not true regarding the foreign body response? First, proteins form the blood and interstitial fluid adsorb to surfaces of the implant. Recruitment of cells comes in, mainly macrophages and neutrophils. With time the material, proteins, and cells get fused. Encapsulation of the foreign material occurs immediately after implantation When thinking about measurement systems, which is correct? The processor detects the input. The sensor can amplify or filter the signal. The input is the end product the user will know. The receiver presents a message that is interpretable.Pharmacodynamic (PD) Response Biomarkers Instructions Group (https://www.ncbi.nlm.nih.gov/books/NBK326791/), a biomarker is used to show that a biological response has occurred in an individual who has been exposed to a medical product or an environmental agent. Match the pharmacodynamic/response biomarker on the left, with the related you can use internet search, FDA According to the FDA-NIH Biomarker Working treatment/disease on the right. Please note that and NIH websites, as well as the on-line library resources. Sweat chloride Response to warfarin treatment International Effect of enzyme replacement therapy for patients with mucopolysaccharidosis type 1 normalized ratio (INR) Response to a B-lymphocyte stimulator inhibitor in patients with systemic lupus erythematosus Viral load Urinary level of glycosaminoglycans Response to cystic fibrosis transmembrane regulator (CFTR) potentiating agents in patients with cystic fibrosis Blood pressure Response to antihyperglycemic agents or…