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what clinical trial phase is the most important?
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- Explain the construction of knockout mice?A couple has a young child who needs a bone marrow transplant. They propose that preimplantation screening be done on several embryos fertilized in vitro to find a match for their child. What do they need to match in this transplant procedure? The couple proposes that the matching embryo be transplanted to the mother’s uterus and serves as a bone marrow donor when old enough. What are the ethical issues (if any) involved in this proposal?Describe the construction of knockout mice?