Q: In Synthesis of Diben zalacetone, why does the reaction end up being fully conjugated at the…
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Q: Draw structures for the carbonyl electrophile and enolate nucleophile that react to give the enone…
A: enolate attacks the carbonyl electrophile and forms enone Generally this is resembles to aldol…
Q: lease explain the mechanism for the ring opening of epoxide by reaction with nucleophile in base
A: Epoxides are called the cyclic ethers. The epoxide rings are very stable. When a nucleophile attacks…
Q: (b) Why is the Claisen-Schmidt reaction a special type of aldol condensation? one of the…
A: Answers of the above questions given below.
Q: How do polar protic and aprotic solvents affect the reactivity of enolates ? 2.
A: Enolate ions Enolate formation can be depicted as; α H present near a carbonyl group is abstracted…
Q: NaOEt, EIOH
A: Firstly we will discuss about Aldol condensation and Aldol Reaction. Aldol condensation name is…
Q: Give the expected products for the aldol condensations of ) phenylacetaldehyde.
A: Aldol condensation reaction- The reaction between two carbonyl compounds which posses α-hydrogen…
Q: Explain the Mechanism of Tautomerization ?
A: In this question, we will explain the mechanism of Tautomerization. You can see details explanation…
Q: enolate base enolate base
A: The first compound contains an active methylene group. The alpha proton carbonyl group is acidic in…
Q: What is the likely mechanism of nucleophilic substitution for attached alkyl halide?
A: As there is no attached alkyl halide in the question. So discuss general mechanism of nucleophilic…
Q: In other reactions, both reactants may have acidic Hydrogens, leading to two different products.…
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Q: Show how enols, enolate ions, andenamines act as nucleophiles
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Q: From the given structures which is (a) an acid halide? (b) a secondary amide (c) an aldehyde…
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Q: Give the reaction mechanism for the following: a. Aldol condensation b. Claisen condensation…
A: In an aldol condensation, the enolate ion combines with a carbonyl molecule to produce a…
Q: Ph= Ph C. ** 3.
A: in basic condition, Carbonyl compound having enolisable alpha Hydrogen, form enolate as follows :…
Q: Explain advantages and disadvantages of Direct enolate alkylation ?
A: Direct enolate alkylation: In this reaction the α hydrogen is replaced by alkyl group resulting in…
Q: Write the reagents and mechanism for synthesizing the aldol product. Hint: the reagents are ketone…
A: Aldehydes and ketones containing at least one alpha-hydrogen atom when treated with dilute…
Q: (1) Which has a single enolizable Hydrogen? (2) Which of the following produces an aldol and an…
A: Aldol condensation reaction- under acidic or basic medium the enolizable beta- hydrogen of carbonyl…
Q: what would produce this ozonolysis
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Q: он но
A: We can begin the conversion from the elimination reaction of the alcohol to give an alkene. The…
Q: What product would you expect from aldol cyclization of hexanediol in basic solution?
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Q: Draw structures for the carbonyl electrophile and enolate nucleophile that react to give the aldol…
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Q: Can 2,4-pentanedione undergo an intramolecular aldol addition? If so, why? If not, why not?
A: Aldol addition in organic chemistry is a chemical reaction in which an enol or an enolate ion…
Q: what enone product would you expect to obtain from aldol condensation of the following compounds
A: (a)
Q: Use the condensation reaction of acetaldehyde (CH3CHO) as an example to show the mechanism of aldol…
A: Aldol condensation Reaction: This reaction is for the aldehydes or ketones which has alpha…
Q: What is the first step in the acid-catalyzed aldol condensation reaction. Attack of the…
A: Hi, we are supposed to answer one question. To get the remaining questions solved please mention the…
Q: Draw the mechanism of the favorable reaction of CH3CO2H and sodium ethoxide (CH3CH2O-Na+) through…
A: Bronsted-Lowry acid-base theory: The Bronsted-Lowry acid-base theory states that the acid is a…
Q: Formaldehyde does not take part in Aldol condensation. Why ?
A: Given Formaldehyde does not take part in Aldol condensation. Why ?
Q: Give the General Reactions of Enolates ?
A: A base is used to remove an acidic hydrogen from the compound.
Q: Explain the Examples of Enolates and Related Anions ?
A: The driving force is the formation of a carbanion which allows the shifting the electron density of…
Q: Define Mechanism - The Intramolecular Aldol Reaction ?
A: Compounds containing two carbonyl underogoes intramolecular aldol reaction if a five or six-membered…
Q: Please draw and explain the mechanism of the formation of epoxide via intramolecular SN2 reaction of…
A: Halohydrins when treated with strong base (such as hydroxide anion) result in the formation of…
Q: Explain the major step of a nucleophilic acyl substitution ?
A: The functional groups that undergo nucleophilic acyl substitutions are called carboxylic acid…
Q: Which one of the mixtures of compounds shown below could be reacted with NaOH/ELOH to give primarily…
A: Ans
Q: Give the major product and the stepwise reaction mechanism for the following acid catalyzed epoxide…
A: Answer:- This question is answered by using the simple concept chemical reaction of epoxides with…
Q: Why are enolates more usful than enols ?
A: Enolates more useful than enols have to be determined.
Q: What is one method for preparing an epoxide and write out the reaction.
A: Epoxide can be prepared by the reaction of an alkene with peroxide like m-CPBA.
Q: Give an example of a proline-catalyzed direct asymmetric aldol reaction
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Q: 1. Why is aldol product the major product in relation to the Cannizzaro reaction?
A: Note: Since you have posted a question with multiple subparts, we will solve the first three…
Q: Consider the following crossed aldol condensation. Which statement explains why a single cross…
A: Given : reaction of cross aldol reaction. For aldol reaction there should be alpha hydrogen.
Q: Why is the enone product favored to be formed under the shown conditions rather than the aldol…
A: E1cB (Elimination Unimolecular Conjugate base) reaction involves the elimination of poor leaving…
Q: The reaction of LDA with the molecule (below) produces: A) an enolate
A:
Q: Illustrate how a directed aldol reaction was used in the synthesis ofperiplanone B, the sex…
A: Periplanone B is a sex attractant.
Q: In the reduction of carbonyl compounds with NaBH4, the nucleophile is ______.
A: Nucleophile is a negatively charged or electron rich species which attacks on the positively charged…
Q: CH3 ннн H H エエ
A: Α-hydrogen of carbonyl compounds are acidic in nature and it is removed in the presence of a base to…
Q: What is the reaction mechanism for this final step in an Aldol Condensation
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Explain the direct method of enolate alkylation ?
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Solved in 3 steps with 2 images
- Define Direct Enolate Alkylation ?1. Provide the mechanism of the reaction shown in the picture. 2. Explain why it cannot be done in basic conditions. 3. Why is the enol tautomer favored over the keto tautomer?What aldol product is formed when two molecules of butanal react together in the presence of base? What reagents are needed to convert this product to each of the attached compounds?
- What types of species are the electrophile and nucleophile in an aldol addition? 1. Nu: ester, E+: carbonyl 2. Nu: carbonyl, E+: carbonyl 3. Nu: carbonyl, E+: ester 4. Nu: ester, E+: esterWhat mechanism produced each product and why/how?Provide the structure of the enamine synthesized from the following reaction. O. COMe + H3O+ Provide the structures of the products and draw the complete curved arrow mechanism for the hydrolysis of the indicated acetal OR imine in aqueous acid. HN-CHO Reaction mechanism: [H+] OR Enamine N H3O+