a)b)OHн How might you carry out the following selective transformations? (Note that a protection step may be required, and recall that aldehydes are more reactive than ketones towardnucleophilic addition.)Syntheses may require several steps.Choose the route with the fewest steps.Use letters from the table to list reagents in the order used (first at the left).Example: dagabCd1. excess NaBH42. H3O*1. 1 eq. NaBH42. H3O*1. LiAlH42. H30*aqueous HCIefgReagents1. Li(CH3)2Cu2. H3O+1. CH3MgBr / dry ether2 H3O+HOCH₂CH₂OH/HCIhijTrimethylsilyl chloride /triethylamineCrO3/H3O+Dess-Martin periodinanein CH₂Cl₂

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Answered: a) b) OH معه

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Chemistry

a) b) OH معه

Organic Chemistry

9th Edition

ISBN:9781305080485

Author:John E. McMurry

Publisher:John E. McMurry

Chapter16: Chemistry Of Benzene: Electrophilic Aromatic Substitution

Section16.SE: Something Extra

Problem 30MP: The carbocation electrophile in a Friede1-Crafts reaction can be generated by an alternate means...

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How would you synthesize the following compounds from cyclohexanone using reagents from the table? Use letters from the table to list reagents in the order used (first at the left). Reagents a 1. CH3MgBr/dry ether 2 H3O+ e 1. OsO4 i 1. BH3/THF 2. NaHSO3/H2O 2. H₂O₂ / NaOH b 1. C6H5MgBr / dry ether f 1. NaBH4 j Mg / dry ether 2 H3O+ 2. H3O+ с PBr3 g HOCH2CH2OH/HCI k H2/Pd d m-chloroperbenzoic h H3O+ / heat I CrO3 / H3O+ acid m cyclohexanone a) cyclohexylbenzene b) 2-phenylcyclohexanone Submit Answer Try Another Version 3 item attempts remaining
How might you carry out the following selective transformations? (Note that a protection step may be required, and recall that aldehydes are more reactive than ketones toward nucleophilic addition.) Syntheses may require several steps. Choose the route with the fewest steps. Use letters from the table to list reagents in the order used (first at the left). Example: dag a) Reagents a 1. excess NaBH4 2. H3O+ e 1. Li(CH3)2Cu 2. H3O+ b 1.1 eq. NaBH4 2. H3O+ f 1. CH3MgBr / dry ether 2 H3O+ C 1. LiAlH4 d. 2. H3O+ aqueous HCI g HOCH2CH2OH/HCI HO CH3 h Trimethylsilyl chloride / triethylamine i CrO3/H3O+ j Dess-Martin periodinane in CH2Cl2 Previous Next>
How would you synthesize the following compounds from cyclohexanone using reagents from the table? Use letters from the table to list reagents in the order used (first at the left). Reagents a 1. CH3MgBr / dry ether 2 H3O+ e 1. OsO4 i 1. BH3/THF 2. NaHSO3/H₂O 2. H₂O₂ / NaOH b 1. C6H5 MgBr / dry ether f 1. NaBH4 j Mg / dry ether 2 H3O+ 2. H3O+ C PBг3 g HOCH2CH2OH/HCI k H2/Pd d m-chloroperbenzoic h H3O+ / heat 1 CrO3 / H3O+ acid a) 2-phenylcyclohexanone b) cyclohexylbenzene m cyclohexanone
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a. When a carboxylic acid is dissolved in isotopically labeled water (H218O) and an acid catalyst is added, the label is incorporated into both oxygens of the acid. Propose a mechanism to account for this. b. If a carboxylic acid is dissolved in isotopically labeled methanol (CH318OH) and an acid catalyst is added, where will the label reside in the product?c. If an ester is dissolved in isotopically labeled water (H218O) and an acid catalyst is added, where will the label reside in the product?
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