. TPCK and TLCK are irreversible inhibitors of serine proteases. One of these inhibits trypsin and the other chymotrypsin. Which is which? Explain your reasoning. "NH, H. ТРСК TLCK

Q: How did analysis of the mechanism of chymotrypsin action help lead to understanding of the action of…

A: Chymotrypsin is a digestive enzyme, one that belongs to the group of serine proteases. Serine…

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Q: If we made a Lineweaver-Burk plot of an irreversible inhibitor, which type of reversible inhibition…

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Q: identify the presence of a peptide bonds in your structure by putting a star/highlighting at the…

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Q: Construct the structure of alpha-lauro-beta-myristolinolenate.

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Q: Determine the pl for this synthesized pentapeptide: A-B-C-D-E Given that the pK values for the amino…

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Q: Circle the correct answer in each sentence. Thus sugar is a (simple ; complex) carbohydrate. The…

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Q: Penicillin binds to transpeptidase thereby preventing enzyme activity. A) If penicillin binds at the…

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Q: Is TMA a volatile compound or a biogenic amine? (explain further) Is the measurement of TMA a…

A: 1. Answer -  TMA is not an amino acid since there is no acidic group in its structure but it is a…

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Q: on derivative curves, there are several sharp peaks. what points in the ionisation of the amino acid…

A: 1. Derivative curve plots the change in pH divided by change in number of moles of the base added,…

Q: Chymotrypsin belowl is a globular protein and is a precursor of the digestive enzyme trypsin in the…

A: Chymotrypsin is a globular protein.  Chymotrypsin is a proteolytic enzyme.  It is synthesised in the…

Q: se inhibitors were s

A: Log1/C = Measure of Biological activity

Q: "There are ten HIV protease inhibitors approved by the FDA; those inhibitors include: saquinavir,…

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Q: In the experiments of Barrick et al. (as shown), it was observed thatreplacement of histidine by a…

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Q: Arginine and lysine side chains fit into trypsin’s binding pocket . One of these side chains forms a…

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Q: If you had a protein X, which is a soluble enzyme found inside the peroxisome, and you wished to…

A: Proteins chain of amino acids which join together to form protein. Proteins are found in the…

Q: the advantages and the disadvantages of the catalyst a) aluminosilicate b) trypsin

A: Advantages of catalyst aluminosilicate - aluminum silicate is basically used to dry oozing and…

Q: 3. If D-serine has a specific activity of +6.83, what will be the specific activity if it is…

A: The specific activity of enantiomers are equal in magnitude but they have opposite signs because…

Q: Noncompetitive inhibition is a limiting case in which the effect of binding inhibitor has no effect…

A: Enzyme inhibitors are of two types depending on their enzyme action They are as follows 1.…

Q: In Hb S, a residue is replaced by a residue. histidine lysine valine

A: given, in Hb S, a ___ residue is replaced by a __ residue.

Q: How is the maximal rate of the enzyme changed in the presence of an inhibitor?

A: Maximum rate of reaction is characteristic of a particular enzyme at a particular concentration and…

Q: What is the K, of the amino acid leucine if it is 34.5% disso- ciated at pH = 9.46? |3D

A: “Since you have asked multiple question, we will solve the first question for you. If you want any…

Q: how many drugs could we test for antitumor activity with a 51x41 grid ofcompounds?

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Q: 1. What is the role of initiator and inhibitor? 2. What are short stops?

A: Since you have posted multiple questions, we will answer only first question for you. If you want…

Q: ular features that stabilize structure. 4. You perform Michaelis-Menten kinetics on (i) trypsin and…

A: a. Specific constant of the enzyme is the indicator of efficiency of the enzymes. The more is the…

Q: peptide

A:

Q: -NH2 Na CN HCL, H,0 CN COCH 2-amino - 3-phenyl propanitrik phenylalanine COOH 02 H20 Iodinase COOH…

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Q: Explain why an irreversible inhibitor of an enzyme might be more toxic to humans than a reversible…

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Q: 5. A histidine residue (His146) in Hb subunit has a side chain pKa of 6.2 in the lung. Due to a…

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Q: II. Analysis. Given below is a schematic diagram for a simple analysis of a novel tetrasaccharide…

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Q: Is gentiobiose a reducing sugar? Does it mutarotate? Explain your reasoning

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Q: 1. In Part II of the Procedure, you were instructed to use your original mixture of phycocyanin and…

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Q: The important steps in solid phase peptide synthesis are? A) Coupling and hydrolysis B) Hydrolysis…

A: Solid-phase peptide synthesis (SPPS) involves the successive addition of protected amino acid and…

Q: What is a protease? Select one: An enzyme that breaks down a protein into individual amino acids A…

A: Protease is an enzyme that breaks down protein into smaller polypeptides or single amino acids. It…

Q: Allosteric proteins a) contain distinct regulatory sites and have multiple functional sites. b)…

A: e) All of the above.

Q: Draw this peptide showing correct stereochemistry (hashed/wedged bonds) and please explain…

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Q: The force constant katr of a backbone Ca – -C bond in a peptide is 250.0 kcal/mol/Angstrom² and the…

A: Given: Force constant (kstr) of bond = 250 Kcal/mol/Angstrom2  Equilibrium bond distance (r0) = 1.49…

Q: There are almost 500 naturally occurring variants of hemoglobin. Hemoglobin X is a hemoglobin…

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Q: Match the words in the left column to the appropriate blanks in The sentences on the right. Reset…

A: In the protein synthesis the inhibitors are the one which delays or stops the growth or…

Q: Test for lipids.

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Q: What is a cost and benefit to denaturing proteins (ie, a pro and a con)?

A: Protein denaturation is a process due to which a protein loses its native shape due to distortion of…

Q: AMINO pKa1 pKa2 ACID Proline 1.99 10.96 Tryptophan 2.38 9.39 Valine 2.32 9.62 Glutamine 2.17 9.13…

A:

Q: An unknown amino acid labeled KEMISTRI has an IpH value equal to 5.41. If its pKa1 is equal to…

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Q: Originally the amino acid itself was considered to be used as a flavor enhancer, but MSG was…

A: Monosodium glutamate (MSG) is the sodium salt of the common amino acid glutamic acid. Glutamic acid…

Q: II. Analysis. Given below is a schematic diagram for a simple analysis of a novel tetrasaccharide…

A: D- fructose  B - glucose  C- galactose  A-ribose  From TLC profile we can see that four…