The normal concentrations for intracellular and extracellular potassium in a neuron are [K+]in = 150 mM and [K+]out = 5 mM, respectively. Due to an electrolyte imbalance, a patient has the following intracellular and extracellular concentrations of potassium: [K+]in = 140 mM and [K+]out =2 mM. Using the Nernst equation (Chapter 4), calculate the equilibrium potential for potassium in the cells with normal K+ distributions and of the diseased patient. Refer back to Question #1. Will it be easier or more difficult to generate an action potential in the diseased neuron as compared to the normal neuron? Why?
The normal concentrations for intracellular and extracellular potassium in a neuron are [K+]in = 150 mM and [K+]out = 5 mM, respectively. Due to an electrolyte imbalance, a patient has the following intracellular and extracellular concentrations of potassium: [K+]in = 140 mM and [K+]out =2 mM. Using the Nernst equation (Chapter 4), calculate the equilibrium potential for potassium in the cells with normal K+ distributions and of the diseased patient. Refer back to Question #1. Will it be easier or more difficult to generate an action potential in the diseased neuron as compared to the normal neuron? Why?
Human Physiology: From Cells to Systems (MindTap Course List)
9th Edition
ISBN:9781285866932
Author:Lauralee Sherwood
Publisher:Lauralee Sherwood
Chapter4: Principles Of Neural And Hormonal Communication
Section: Chapter Questions
Problem 3SQE
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![The normal concentrations for intracellular and extracellular potassium in a neuron
are [K+]in = 150 mM and [K+]out = 5 mM, respectively. Due to an electrolyte
imbalance, a patient has the following intracellular and extracellular concentrations
of potassium: [K+]in = 140 mM and [K+]out =2 mM. Using the Nernst equation
(Chapter 4), calculate the equilibrium potential for potassium in the cells with
normal K+ distributions and of the diseased patient.
Refer back to Question #1. Will it be easier or more difficult to generate an action
potential in the diseased neuron as compared to the normal neuron? Why?](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F0f1fd340-6178-454b-aea7-37c134c266b7%2F88af6af6-ceb9-4c6d-8cde-51241f396271%2F45u62vb_processed.png&w=3840&q=75)
Transcribed Image Text:The normal concentrations for intracellular and extracellular potassium in a neuron
are [K+]in = 150 mM and [K+]out = 5 mM, respectively. Due to an electrolyte
imbalance, a patient has the following intracellular and extracellular concentrations
of potassium: [K+]in = 140 mM and [K+]out =2 mM. Using the Nernst equation
(Chapter 4), calculate the equilibrium potential for potassium in the cells with
normal K+ distributions and of the diseased patient.
Refer back to Question #1. Will it be easier or more difficult to generate an action
potential in the diseased neuron as compared to the normal neuron? Why?
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