Table 2. Summary of Ebola Virus Weapons Ebola Virus Weapon Lipid envelope originating from the host cell that has GP attachment proteins. VP35 GP Mechanism unknown Role in Evading the Immune Response Turns off existing interferon alarms by disrupting STATI signaling pathway. Counteracts tetherin to allow viruses to bud from the cell. Induces bystander apoptosis of immune cells (especially T lymphocytes and NK cells).

Table 2. Summary of Ebola Virus Weapons Ebola Virus Weapon Lipid envelope originating from the host cell that has GP attachment proteins. VP35 GP Mechanism unknown Role in Evading the Immune Response Turns off existing interferon alarms by disrupting STATI signaling pathway. Counteracts tetherin to allow viruses to bud from the cell. Induces bystander apoptosis of immune cells (especially T lymphocytes and NK cells).

Principles Of Pharmacology Med Assist

6th Edition

ISBN:9781337512442

Author:RICE

Publisher:RICE

Chapter16: Antifungal, Antiviral, And Immunizing Agents

Section: Chapter Questions

Problem 19RQ

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