age Individuals who carry stable pericentric inversions are typically phenotypically normal, but have an increased risk of miscarriage leading to reduced fertility. The most likely explanation for this phenomenon is... Select one: O a. Crossing over within the inversion leads to incomplete and unbalanced gametes that are inviable O b. There is an increased risk of a Robertsonian translocations leading to chromosomal trisomy. O c. There is a decreased rate of gamete formation. O d. It leads to polyploidy, which is not tolerated in human fetuses O e. Cells containing the inversion do not go through meiosis ] Next page

age Individuals who carry stable pericentric inversions are typically phenotypically normal, but have an increased risk of miscarriage leading to reduced fertility. The most likely explanation for this phenomenon is... Select one: O a. Crossing over within the inversion leads to incomplete and unbalanced gametes that are inviable O b. There is an increased risk of a Robertsonian translocations leading to chromosomal trisomy. O c. There is a decreased rate of gamete formation. O d. It leads to polyploidy, which is not tolerated in human fetuses O e. Cells containing the inversion do not go through meiosis ] Next page

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Description: pageIndividuals who carry stable pericentric inversions are typically phenotypically normal, but have an increased risk of miscarriage leading to reduced fertility. The mostlikely explanation for this phenomenon is...Select one:O a.Crossing over wit

BIOLOGY:CONCEPTS+APPL.(LOOSELEAF)

10th Edition

ISBN:9781305967359

Author:STARR

Publisher:STARR

Chapter14: Human Inheritance

Section: Chapter Questions

Problem 2GP: Human females have two X chromosomes XX; males have one X and one Y chromosome XY. a. With respect...

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The majority of nondisjunction events leading to Down syndrome are maternal in origin. Based on the duration of meiosis in females, speculate on the possible reasons for females contributing aneuploid gametes more frequently than males do.
Chromosomal nondisjunction of the X chromosome in female gametes of humans means that live offspring can include Select one: O A. females with XX, and males with XY or XO O B. females with XX or XXX, and males with XY or XO O C. females with XX or XXX, and males with XY or XXY O D. females with XX, and males with XY E. females with XX or XO, and males with XY or OY
Down syndrome (trisomy 21) and Edwards syn-drome (trisomy 18) are the most common autosomal triso-mies seen in human infants. Does this fact mean that thesechromosomes are the most difficult to segregate properlyduring meiosis?
Consider an individual with genotype P/p; Q/q. Assume no crossing over. What is the total number of possible genotypes of gametes that may be produced by this individual?
Though an individual with abberations such as Robertsonian translocation may be phenotypically normal, they can generate gametes through meiosis that have atypical organizations of chromosomes, resulting in recurrent fetal abnormalities or miscarriages. Why, despite these Robertsonian translocations, are affected cells still able to generate typical gametes through meiosis?
Table shows that Turner syndrome occurs when an individualinherits one X chromosome but lacks a second sex chromosome.Can Turner syndrome be due to nondisjunction duringoogenesis, spermatogenesis, or both? If a phenotypically normalcouple has a color-blind child (due to a recessive X-linkedallele) with Turner syndrome, did nondisjunction occur duringoogenesis or spermatogenesis in this child’s parents? Explainyour answer.
An individual heterozygous for a reciprocal translocation possesses the following chromosomes: A B ● C D E F G, A B • C D V W X, R S •T U E F G, R S•T U V W Xa. Draw the pairing arrangement of these chromosomes in prophase 1 of meiosis. Mention their gametic composition. b. Draw the alternate, adjacent I, and adjacent II segregation patterns in anaphase I of meiosis. Mention their gametic composition.
Crossing over involves each of the following with the exception of…
Meiotic nondisjunction is much more likely than mitotic nondisjunction.Based on this observation, would you conclude that meioticnondisjunction is usually due to nondisjunction during meiosisI or meiosis II? Explain your reasoning?
A family has an X-linked dominant form of congenital generalizedhypertrichosis (excessive hairiness). Although the allele is dominant,males are more severely affected than females. Moreover, the womenin the family often have asymmetrical, hairy patches on their bodies.How does X chromosome inactivation explain this observation?
A young couple is planning to have children. Knowing that there have been a substantial number of stillbirths, miscarriages, and fertility problems on the husband’s side of the family, they see a genetic counselor. A chromosome analysis reveals that, whereas the woman has a normal karyotype, the man possesses only 45 chromosomes and is a carrier of a Robertsonian translocation between chromosomes 22 and 13. a. List all the different types of gametes that might be produced by the man. b. What types of zygotes will develop when each of gametes produced by the man fuses with a normal gamete produced by the woman? c. If trisomies and monosomies entailing chromosomes 13 and 22 are lethal, approximately what proportion of the surviving offspring are expected to be carriers of the translocation?
A diploid (2n) trihybrid individual with the genotype AaBbDd can make eight genetically different gametes. 2n = 4 n = 2 (1) A d. ID 1 1 2 2 Gt: AaBbDd Loci A/a and D/d are on chromosome 1 and locus B/b is on chromosome 2. Explain how a gamete containing the alleles A, D and b may be produced by meiosis. Refer specifically to meiotic events occurring during Prophase I, Metaphase I, Anaphase I and Anaphase II. (NB: remember to refer to the organism above). CO