Zach is conducting experiments investigating transplantation. He mates a female (mom, with the homozygous MHC haplotype of b, with a male (dad), with the homozygous MHC haplotype of k. The mating is fruitful and subsequently four offspring were born: Sib1, Sib2, Sib3, and Sib 4. He then performs the following four skin grafts: graft 1) skin from mom (donor) to sib1 (recipient). graft 2) skin from dad (donor) to sib3 (recipient). graft 3) skin from sib4 (donor) to mom (recipient),and graft 4) skin from sib4 (donor) to sib2 (recipient). Which of the following statements below is false? Ograft 2 will be accepted O Sib4 and mom will have an MHC haplotype in common O Sib4 is polymorphic at the MHCII locus We are unable to predict whether graft number 1 will be accepted

Zach is conducting experiments investigating transplantation. He mates a female (mom, with the homozygous MHC haplotype of b, with a male (dad), with the homozygous MHC haplotype of k. The mating is fruitful and subsequently four offspring were born: Sib1, Sib2, Sib3, and Sib 4. He then performs the following four skin grafts: graft 1) skin from mom (donor) to sib1 (recipient). graft 2) skin from dad (donor) to sib3 (recipient). graft 3) skin from sib4 (donor) to mom (recipient),and graft 4) skin from sib4 (donor) to sib2 (recipient). Which of the following statements below is false? Ograft 2 will be accepted O Sib4 and mom will have an MHC haplotype in common O Sib4 is polymorphic at the MHCII locus We are unable to predict whether graft number 1 will be accepted

Basic Clinical Laboratory Techniques 6E

6th Edition

ISBN:9781133893943

Author:ESTRIDGE

Publisher:ESTRIDGE

Chapter7: Basic Clinical Microbiology

Section7.8: Tests For Sexually Transmitted Diseases

Problem 8RQ

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If transplanting a solid organ such as a kidney, why is MHC II matching also important to success of the graft?
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