You visit a huge city with millions of people. If you were to start sampling the cystic fibrosis allele from one generation to the next, what should happen to its frequency over the next few generations, and why?
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- A mutation in an of the recessive hemoglobin gene on chromosome 11 causes sickle-cell disease, but also confers malaria resistance. The allele frequency in African Americans is 14%. 1. What percent of the population have two copies of the gene and are therefore immune to malaria? 2. What percent of the population are less susceptible to malaria but do not have sickle-cell anemia since they are heterozygous?The agouti gene determines coat colour in mice. Heterozygous mice have yellow coats, while homozygous dominant mice have black coats. However, having two copies of the recessive alleles is lethal. In a population of 2 000 mice, 1 082 mice have black coats. a) Calculate the frequency of each allele. Show all your work and express your answer as a value between 0 and 1 rounded to two decimal places. b) What percentage of the mouse population is expected to be carriers of the lethal allele? Show all your work and express your answer rounded to one decimal place. c) How many mice will die during fetal development? Show all your work and round your answer to the closest whole number.Cystic fibrosis is an autosomal recessive disorder that affects 1 in 3 000 newborns with Caucasian background. It causes thick mucus build up in various organs and can cause damages and problems in respiratory and digestive systems. a) What is the frequency of the cystic fibrosis allele in the Caucasian population? Show all your work and express your answer as a value between 0 and 1 rounded to two decimal places. b) What percentage of the Caucasian population would be carriers for cystic fibrosis? Show all your work and express your answer rounded to two decimal places. c)If two individuals are carriers of the cystic fibrosis allele, what is the probability that they would have a girl without cystic fibrosis? Show all your work (including the Punnett square) and express your answer as a value between 0 and 1 rounded to two decimal places.
- About 4 percent of people of Northern European descent have a cystic fibrosis allele, but only about 1 in 2,500 of these people actually has the disorder. What is the most likely reason for this finding?The gel image below shows 7 alleles, let’s call them 1-7 in order of size, with 1 being the largest and 7 being the smallest. In this sample of 11 individuals, how many times does allele 5 appear?Below is a pedigree of a human blinding disease. Use this pedigree to answer the following questions. If this is disease has an autosomal recessive inheritance pattern, what is the probability that if individuals IV-5 and III-5 had and offspring it would exhibit the disease? a) 25% b) 33% c) 11% d) 17% e) 6%
- Malaria is a leading cause of human illness and mortality worldwide, with 200 million people infected and 600,000 deaths each year. In the 1960s, the incidence of malaria was reduced owing to the use of insecticides that killed mosquitoes in the genus Anopheles, which transmit the disease from person to person. But today, mosquitoes are becoming resistant to insecticides--causing a resurgence in malaria. In this exercise, you will investigate whether alleles encoding resistance to insecticides have been transferred between closely related species of Anopheles. To find out whether transfers have occurred, you will analyze DNA results from two species of mosquitoes that transmit malaria (Anopheles gambiae and A. coluzzii) and from A. gambiae × A. coluzzii hybrids. Resistance to DDT and other insecticides in Anopheles is affected by a sodium channel gene, kdr. The allele r of this gene confers resistance, while the wild type (+/+) genotype is not resistant. Researchers sequenced the kdr…The gel image below shows 7 alleles, let’s call them 1-7 in order of size, with 1 being the largest and 7 being the smallest. In this sample of 11 individuals, how many times does allele 3 appear? Please type your answer as a number, not a word. ANSWER: In the image below allele 3 appears ? times.You are studying a new allele of the yellow gene in pea plants (the gene that in Mendel’s experiments gave green peas with the yy allele combination). You refer to this new allele as y2. When you look at y2y2 homozygotes, you find that 80% of the peas are some shade of green and of these green peas 50% of them are the same full green shade as Mendel’s original yy allele and 50% of them are a shade that is halfway between yellow and green. Discuss these properties in terms of expressivity and penetrance.”
- You are doing a genetics experiment with the fruit fly. In the “P” generation, you cross two true-breeding flies. The female parent is brown and wingless and the male parent is black with normal wings. All of the flies in the F1 generation are brown and have normal wings. Answer all the questions below. 3d. You count 1600 offspring in the F2 generation. If the wing and the color traits were linked and no recombination occurred, what would you expect the numbers of: 1. brown winged flies (BbNn) 2. black winged flies (Bbnn) 3. brown wingless flies (bbNn) 4. black wingless flies (bbnn). 3e. What is the genetic distance between the color and wing genes when you count the F2 generation as 85 brown winged flies, 728 black winged flies, 712 brown wingless flies, and 75 black wingless flies.population is black in colour but about 1/4 of them are white. gene (B) that produces an enzyme that converts a pigment molecule to produce the Black colour. There are 2 alleles of this gene - the dominant B and the recessive b. DNA analysis shows that black individuals have either a BB or Bb genotype and that white individuals have a bb phenotype. However, you have discovered that a small percentage of White individuals have either a BB or Bb genotype. Explain two reasons that could explain this apparent anomaly. They have a BB or Bb genotype but a white phenotype.After graduation, you and 19 of your closest friends charter a plane to go on a round-the-world tour. Unfortunately, you all crash land safely on a deserted island and you start a new population totally isolated from the rest of the world. Two of your friends are heterozygous for the recessive cystic fibrosis allele (c). Assuming that the frequency of this allele does not change as the population grows, what will be the incidence of cystic fibrosis on your island? In percentage provide summation.