Which should be more reactive for an SN2 reaction involving sodium iodide in a solution of acetone, 2-chlorobutane or 1-chlorobutane?

Q: Why isn’t FeBr3 used as a catalyst in the first step of the synthesis of 1,3,5-tribromobenzene?

A: Amine group of aniline is a strong activating substituent. It donates electrons to the ring by…

Q: Grignard reagent formation may not be successful in which one of the following solvents:

A: We need to find in which of given solvents grignard reagent formation is not successful

Q: tert-Butyl chloride (2-chloro-2-methylpropane) can undergo both the E1 and the SN1 reactions.  Given…

A: Answer  Given that the solvent is ethanol, what will the E1 product be

Q: why is tylenol ( acetaminophen) not a good nucleophile to make a good nuclophile what reaction does…

A: Using Williamson ether synthesis we can synthesized phenacatin from tylenol.  Tylenol is not good…

Q: Which solvent would have a higher reaction rate for SN1? acetone ethanol Why does the solvent you…

A: Ethanol is a polar solvent that is used in SN1 reactions.

Q: 1. Why was the purpose of the tube packed with calcium chloride in the Williamson Ether Synthesis?

A: 1. Answer - Williamson ether synthesis This  is an organic reaction, forming an ether from an…

Q: Why is a sulfonate anion such a good leaving group?

A: Those species which are weak base are good leaving group because they are poor electron donors. If…

Q: 17. Which type of solvent/s would be best for the Sn1 reaction? Explain why.

A: The SN1 reaction is a Nucleophilic Unimolecular substitution reaction.

Q: In the Iodination of Acetone, What will happen to the reaction time and reaction rate if the…

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Q: What is the chemical composition of the nitrating mixture? Why does the incoming nitro group go para…

A:

Q: Explain the effect of protic solvents in SN1 Reaction.

A: The effect of protic solvents in the SN1 Reaction has to be explained below.

Q: Rank these substrates from most to least reactive in an SN2 reaction and give a brief rationale for…

A: SN2 reaction is a nucleophilic substitution reaction in which the nucleophile will attack from…

Q: Which side reaction could occur in this experiment if the toluene were not com- pletely dry? Show…

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Q: Explain how these Grignard reagents would react with molecules of their own kind to “self-destruct.”

A: Given reagent,

Q: turbo-Grignard reaction, please tell me the reason for reacting 2-chloropropane first. After that,…

A: The Grignard reagent is expressed as RMgX, Where R can be an alkyl or aryl group and X is a halogen…

Q: Why is it necessary to exclude moisture in the Grignard reaction?  Be specific.  What happens to the…

A: Alkyl halides in presence of Mg metal and dry ether form alkyl magnesium halides (RMgX) which are…

Q: In the bromination of toluene, why is the reaction faster when using acetic acid as the solvent…

A: Bromination of toluene occurs by aromatic electrophilic substitution reaction.

Q: why it is not a good idea to use dichloromethane as a solvent in Grignard reactions.

A: Reason for not using dichloromethane as a solvent in Grignard reactions.

Q: Based on the theoretical result, what is the order of reactivity of primary, secondary, and tertiary…

A: 1.  Reaction of alkyl halide with NaI, acetone is a SN2 reaction. The order of stability of alkyl…

Q: Will potassium tert-butoxide eliminate the fluoride or bromide from 2-bromo-1,1,1,-fluoro-3-methyl…

A:

Q: What is the difference between activated pyridine and unactivated pyridine

A: Pyridine is a pi difficient heterocycle, pyridine ring is less nucleophilic than the benzenering…

Q: Compare the function of the solvent (methanol) in the E1 and SN1 reactions.

A: In SN1 and E1 reactions, a carbocation is formed as an intermediate.

Q: Briefly explain why OtBu- sometimes favored over hydroxide as an elimination reagent?

A:

Q: Which solvent would be the best choice (DMF, methanol, or acetic acid) to carry out the nucleophilic…

A: There are different types of nucleophilic substitution reaction-  1- SN1 reaction 2- SN2 reaction

Q: Why is the major product for 2-butanol and HCl achieved via SN1 and not E1 or SN2?

A: The reactants given are 2-butanol and HCl. And the reaction mechanism is SN1.

Q: Based on the theoretical result, what is the order of reactivity of primary, secondary, and tertiary…

A: In presence of sodium iodide in acetone, alkyl halide reacte in SN2 mechanism.

Q: Briefly explain why diethyl ether is the solvent of choice for Grignard reactions.

A: Grignard reagents are the reagents which have the formula RMgX. Hence the grignard reagent is an…

Q: How does changing the solvent from DMSO to CH3OH affect the rate of an E1 reaction?

A: E1 reaction stands for unimolecular elimination reaction. As the name suggests these reactions…

Q: Why can aniline not be brominated directly to 4-bromoaniline?

A: In aniline, -NH2 group is both para and ortho directing group due to resonance effect. Since, the…

Q: Complete these reactions involving lithium diorganocopper (Gilman) reagents

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Q: Give a reason why the reduction reaction (with H2, Pt) of nitrobenzene to aniline is so important.

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Q: I wanted to know why the Suzuki reaction can take place in aqueous solution whereas a Grignard…

A:

Q: Please explain how you came about your answer for these questions

A: unsaturated compounds addition with  excess amount of HBr to give corresponding saturated compounds.…

Q: Complete the  reaction  involving lithium diorganocopper (Gilman) reagents

A: A new C-C bond is formed between atoms when an alkyl halide is treated with Gilman reagent or…

Q: Which one of the following solvents is the best choice for SN2 reaction? cyclohexane water hexane O…

A: The solvent which is used in SN2 reaction is given below.

Q: In this E1 reaction, why is it wrong to have include the alcohol and methyl group on the secondary…

A: The reaction in which substituents are removed is known as elimination reaction. The reaction occurs…

Q: Which should be more reactive for an SN2 reaction involving sodium iodide in a solution of acetone,…

A: SN2 Reaction is a nucleophilic substitution reaction in which the rate determining step depends on…

Q: why is the temperature cooled to 100degree celcius in the reaction of benzil and 1,3dipenhyl acetone…

A: The mechanism involved in the reaction between benzil and 1,3-diphenylacetone is given by

Q: Why do the nitro groups change the relative leaving tendencies of the carboxy and 2,4-dinitrophenoxy…

A: Nucleophilic substitution tendencies of aromatic rings are enhanced by the electron withdrawing…

Q: In bromination of e-stilbine, what is the purpose of adding potassium bisulfate, glacial acetic…

A: Since you have asked multiple questions, we will solve first one for you. For remaining question,…

Q: What is the best type of solvent for an E2 and an E1 reaction? Please define the terms

A: Both are the elimination reactions with small changes.  E1 proceeds in two steps and E2 proceeds in…

Q: In the Janovsky reaction, explain why the meta-dinitrobenzene acts as an electrophile. What is the…

A: In Janovsky reaction, aldehydes and ketones with α-methylene groups react with m-dinitrobenzene in…

Q: Explain how these Grignard reagents would react with molecules of their own kind to “self-destruct.”

A: 3-Hydroxypropylmagnesium bromide has an acidic proton (the alcohol). Because Grignard reagents are…

Q: Friedel-Crafts Alkylation, based on substituted benzene reaction, including reactivity based on…

A: A question based on Friedal-Craft alkylation reaction, which is to be accomplished.

Q: Give a reason why the redution reaction (with H2, Pt) of nitrobenzene to aniline is so important.

A: Reduction means addition of Hydrogens to The functional group.

Q: To what structural effect would you attribute the preference of methyl bromide over t-bromyl bromide…

A: To what structural effect would you attribute the preference of methyl bromide over t-bromyl bromide…

Q: The SN2 reaction can be carried out intramolecularly (in the same molecule). What product do you…

A:

Q: Complete these reactions involving lithium diorganocopper (Gilman) reagents

A: Gilman reagent The reagent which has the form R2CuLi, where R is alkyl group. In the reaction,…

Q: Complete the electron pushing mechanism for the E1 reaction when 2‑methylbutan‑2‑ol is treated with…

A: A question based on E1 reaction, which is to be accomplished.