What is the mechanism by which these designed nucleases cause a change in the genomic DNA sequence?
Q: What are the two basic types of transposons?
A: Transposable element is otherwise known as transposons and they are characterized by the DNA segment…
Q: What is the name of the DNA duplication process? What is the main enzyme that participates in it?
A: Every living cell divides to form multiple cells. During this division process, there is another…
Q: What is the purpose of DNA methylation? Why is it ineffective in the DNA repair of spontaneous…
A: DNA methylation is the process of adding methyl groups to DNA at Nucleotide bases, so that without…
Q: Why is only one strand transcribed, and is the same strand of DNAalways transcribed?
A: DNA (Deoxyribo Nucleic Acid) is the genetic material in all the prokaryotes are eukaryotes. DNA is…
Q: What mutations are possible in gene ZFPM2?
A: ZFPM 2 is a multi zinc finger protein. It helps in transcription regulation of certain genes by…
Q: How are the repeated sequences generated?
A: Introduction Repeated sequences are patterns of nucleic acids (DNA/RNA) that occur at multiple sites…
Q: What are artificial chromosomes and why are they used?
A: A chromosome is a thread like structure present within the living cells. It contains the genetic…
Q: Can methylation of nucleotides play a role in DNA replication? If so, what sort of role?
A: Deoxyribonucleic acid (DNA) involves the addition of methyl group to the DNA molecule and it can…
Q: What is the Evidence for a triplet code?
A: DNA is the genetic material in most living organisms. It is the information hub of the cell that…
Q: How can these designed nucleases alter the sequence of the genomic DNA?
A: The Common approach to understand gene function in a systematic and unbiased way is including…
Q: What is the genetic basis that causes the symptoms of Downsyndrome?
A: Genetic diseases can be defined as the diseases which is cause due to the change in the genetic…
Q: Why is the term “proteome” ambiguous, whereas the term“genome” is not?
A: The proteins are the essential part of living organisms and it consists of thousands of smaller…
Q: What is the chemical composition of the genetic material?
A: To define: To explain the chemical composition of the genetic material and the code structure
Q: What is the process of DNA, RNA, and proteins (in that order) and what is the function of them? Why.…
A: Introduction Central Dogma: it is the key mechanism by which DNA can be transcribed into mRNA by the…
Q: Why do A-T base pairs inhibit left-handed DNA formation?
A: The capacity of nucleic acids to guide their own reproduction from monomers makes them unique.…
Q: How do these engineered nucleases effect a change in the genomic DNA sequence?
A: Genome editing is a technique used to precisely and efficiently modify DNA within a cell. It…
Q: What is the major form of DNA methylation that is seen in eukaryotes? At what type of DNA sequence…
A: Step 1 Deoxyribonucleic acid (DNA) methylation is am epigenetic procedure that takes place by adding…
Q: What mutagen causes thymine dimers, and why does it kill cells?
A: A mutation occurs/happens when the sequence/structure of DNA changes. Mutations can occur/happens as…
Q: Why are transposable elements often called genomic parasites?
A: Transposable elements, also known as jumping genes are short segments of DNA, which have special…
Q: How many transposons are in the human genome?
A: Transposons or transposable elements (TE) are the DNA (deoxyribonucleic acid) sequences that can…
Q: What is the architecture of the DNA polymerases and the replisome?
A: Gene is the unit of heredity. Living organisms contain genetic materials mainly made up of nucleic…
Q: What is the function of histones in DNA packiging?
A: The DNA (deoxyribonucleic acid) is a two-fold helical structure with two polynucleotide strands…
Q: What are DNA methyltransferases (DNMTS) ?
A: Enzymes are protein molecules that aid in increasing the rate of metabolism and chemical reactions…
Q: What is chromosome 12 deletion effects?
A: Chromosomes are long thread-like structures that carry coded genetic information in the form of DNA.…
Q: What effect does histone acetylation have on Gene 1?
A: Histone acetylation is an epigenetic modification of transcription . Histone acetylation is the…
Q: What are genomic variants?
A: The term variant is often used to refer to a specific region of the genome which differs between two…
Q: What mutagen results to the formation of thymine dimers?
A: Asked : Mutagen which results to the formation of thymine dimers
Q: How many exons has the CFTR gene?
A: Introduction :- The CFTR gene encodes a membrane protein and chloride channel in vertebrates called…
Q: Do DNA-polymerase enzymes also function as exonucleases?
A: DNA polymerase enzyme is primarily responsible for the synthesis of DNA by the attachment of various…
Q: How do type IA, type IB, and type II topoisomerases alter DNA topology?Which processes require the…
A: Enzyme is a catalytic molecule that increases the rate of any chemical reaction without being used…
Q: What is a complex of proteins that folds up the telomeres into a structure that shields…
A: A complex of protein is generally found in many eukaryotic cell, whose primary function is the…
Q: What is the enzyme responsible for methylating DNA? How does a drug like doxorubicin affect DNA…
A: DNA is the nucleic acids present in the organisms. DNA is the deoxy ribose nucleic acid in which…
Q: How many codons are there in the mutated DNA-(b) and DNA-(c)? What types of mutations occurred in…
A: Codon is sequences of three DNA or RNA nucleotides.
Q: How can these designed nucleases modify the sequence of genomic DNA?
A: A nuclease is a protein that can break the phosphodiester links between nucleotides in nucleic…
Q: What are DNA methyltransferases (DNMTs) ?
A: Enzymes are referred to as the molecules of proteins that help in increasing the metabolism rate and…
Q: What are the variable number of tandem repeats?
A: Variable number of tandem repeats (VNTR) are regions in the genome where a short nucleotide…
Q: How do we know that DNA synthesis is discontinuous on one of the two template strands?
A: DNA replication refers to the process of making two identical copies of a DNA molecule. This…
Q: Which are the two basic types of transposons?
A: Transposons are also known as jumping genes or transposable element. It is a special type of…
Q: In genetic transformation, what is meant by the wordcompetence?
A: The process of taking up naked or foreign deoxyribonucleic acid (DNA) from the environment is called…
Q: How do these designed nucleases modify the genomic DNA sequence?
A: Designer nucleases functions by targeting a specific DNA sequence with in a genome.
Q: What is a nucleosome-free region? Where are such regions typically found in a genome? How are…
A: Given: Explain about the nucleosome-free region. and explain such regions typically found in a…
Q: How are flanking direct repeats created in transposition?
A: When the genes become capable to switch over their position on chromosome then it is called…
Q: Why is a chromosomal fragment without a centromeresubsequently lost and degraded?
A: The changes in the structure of the chromosome and genes are called chromosomal mutations. The…
Q: What are the similarities a chromosomal mutation and point mutation?
A: Chromosomal mutation is a numerical or structural change in a chromosome. It causes Klinefelter…
What is the mechanism by which these designed nucleases cause a change in the genomic DNA sequence?
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- What are DNA methyltransferases (DNMTs) ?Since eukaryotic chromosomes are assembled with histone proteins, how are replication and transcription carried out? Describe the mechanisms.What is the result when the core histones are acetylated via histone acetyltransferase? A) The result depends on which histone is modified. B) The DNA becomes more tightly associated with the core. O C) The DNA becomes less associated with the core. This modification has no effect on how tightly associated DNA will become with the core.
- During the process of transcription, the polymerase must handle several distinct polynucleotide chains: the double-stranded DNA ahead of the polymerase, the single-stranded template DNA, the nontemplate DNA strand, and the freshly-synthesized mRNA. How does the polymerase keep each of these strands--as well as the incoming ribonucleotides needed for the polymerase reaction--separate?Does a gene sequence carry a mutation that might cause adisease?What is the difference in the requirement for a primer in RNA transcription compared to DNA replication?
- The following sequence represents a few codons present in one strand of DNA.Using this strand of DNA as a template strand for transcription, you are required to synthesize a new RNA strand. A) Show the codons that will be present on the RNA strand. B) Using the universal genetic code, provide the amino acids on the protein that will be translated from the RNA strand. 3’ TAC ATG GTT GTG CTA ATT 5’What are nucleosomes composed of, and how do they participate in the coiling of DNA?What is the function of telomerase?
- How do type IA, type IB, and type II topoisomerases alter DNA topology?Which processes require the input of free energy?If an extra nucleotide is inserted in the first exon of the beta globin gene, what effect will it have on the amino acid sequence of the globin polypeptides? Will the globin most likely be fully functional, partly functional, or nonfunctional? Why?What percentage of the DNA in the genome actually corresponds to genes? How much is actually protein-coding exons? What makes up the rest?