What is the likely problem with doing a diethyl ether/water extraction on the following reaction product to isolate product E in the diethyl ether layer? What is the reason for the problem? 1) NaBH₁/MeOH 2) Mild acid ногих HO Product E лон OH

What is the likely problem with doing a diethyl ether/water extraction on the following reaction product to isolate product E in the diethyl ether layer? What is the reason for the problem? 1) NaBH₁/MeOH 2) Mild acid ногих HO Product E лон OH

Organic Chemistry

8th Edition

ISBN:9781305580350

Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Chapter18: Functional Derivatives Of Carboxylic Acids

Section: Chapter Questions

Problem 18.12P

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Concept explainers

Diol

In chemistry there are so many chemical compounds that have a hydroxyl group but a chemical compound having two hydroxyl groups (-OH) is termed as a diol. It also implies the presence of two alcohols whereas polyols contain two or more than two hydroxyl groups (-OH). Glycol or 1,2-diol is an aliphatic diol that has two alcohol groups on adjacent carbon atoms. In industries, the most commonly used diol is ethylene glycol.

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What is the likely problem with doing a diethyl ether/water extraction on the following reaction
product to isolate product E in the diethyl ether layer?
What is the reason for the problem?
CO
:O
1) NaBH₁/MeOH
2) Mild acid
HO
Product E
OH
OH

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