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- is thal ui ANensn hilia is an inherited genetic disorder linked to the nosome that results in ineffective blood clotting when a blood is damaged. The most common type, hemophilia A, occurs 5000 male births. Any male who carries the gene will express enotype. Hemophilia is extremely rare in women. Parents Carrler female Normal male couple wish to have children. The woman knows she a rrier for hemophilia. The man is not a hemophiliac. Use e notation Xh for hemophilia and XH for the dominant ele to complete the diagram on the right including the arent genotypes, gametes and possible fertilizations. rite the genotypes and phenotypes in the table below. XY XhXh Gametes Xh Xh Genotypes Phenotypes Possible lertilizations Male children XhY Xhx XhY XhX Paternal gametes Paternal gametes Female children 00 00 A second couple also wish to have children. The woman knows her maternal grandfather was a hemophiliac, but neither her mother or father were. Determine the probability she is a carrier…D. Sex-linked In humans, hemophilia is a sex-linked trait. Females can be normal, carriers, or have the disease. Males will either have the disease or not (but they won't ever be carriers). 1. Show the cross of a man who has hemophilia with a normal woman. What is the probability that their children will have the disease? H H = female, normal H h X X = female, carrier h xxn XHY X" Y 2. A woman who is a carrier marries a hemophiliac man. Show the cross. What is the probability that their children will have hemophilia? What sex will a child in the family with hemophilia be? 3. A woman who has hemophilia marries a normal man. How many of their children will have hemophilia, and what is their sex? = female, hemophiliac = male, normal = male, hemophiliacWhat is the karyotype for men who have an extra Y chromosome? Discuss all the ways you can test for this abnormality.
- An A+ male impregnates a woman who is unsure of her blood type. Which blood type would the mother have to be for the baby to be at risk of a hemolytic disease?1. A woman who is heterozygous for hemophilia marries a man with hemophilia. What are the genotypes and phenotypes of the children? a) What is the genotypic ratio of the above cross (Write number next to genotype)? ___________________________________________________________________ b) What is the phenotypic ratio of the above cross? (Write number next to phenotype)? ___________________________________________________________________A phenotypically normal man, who has a hemophiliac brother, marries a normal woman, who is not a carrier. What is the probability that any of their children will be hemophiliac?
- Hemophilia is a sex-linked disorder, where XH = normal gene (no hemophilia) and Xh = hemophilia. A heterozygous female is crossed with an unaffected male. Complete the Punnett square and answer the questions from the parent cross (X#xh mates XHY). XH xh What is the probability of having a child with hemophilia? What is the probability of having a male child with hemophilia? Y What is the probability of having a female child with hemophilia? : xHxh : x*xh : xHy : xhY :: 0% :: 25% :: 50% :: 75% :: 100%Hemophilia is due to a sex-linked gene. It is recessive and found on the X chromosome. A woman who is a carrier for hemophilia marries a normal man. What will be the possible phenotypes of their children? (use the letter “H”)A man with hemophilia has a daughter of normal phenotype. She marries a man who is normal for the trait. The probability of their son to be a hemophiliac is 1/4. Its true or false? Explain.
- Tell me whether it is autosomal reccessive inheritance,autosomal domiant inheritance,sex-linked reccessive inheritance, sex-linked dominay inheritance or y-linked inheritance.Normal No Spac Hemophilia is a blood clotting disorder that almost exclusively affects males. It is a sex-linked, recessive disorder (X). Using the details below, fill in the Punnett square to determine the percent probability of the couple having a child with hemophilia. Mother Father -carrier of -does not have hemophilia hemophilia -genotype XHX -genotype XY Mother. XH. Xh Father Probability of offspring having hemophilia: OFocusAaBBdd x AaBbDd punnet square genotype phenotype