What is the difference between Cockroft gault formula and Ckd-epi creatinine equation? Does both measures creatine clearance? What is more accurate to use?
What is the difference between Cockroft gault formula and Ckd-epi creatinine equation? Does both measures creatine clearance? What is more accurate to use?
Chapter20: Iv Medication And Titration Calculations
Section: Chapter Questions
Problem 24SST
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What is the difference between Cockroft gault formula and Ckd-epi creatinine equation? Does both measures creatine clearance? What is more accurate to use?
Based on the table below, what would be the recommended dosage of "Levofloxacin 500 mg IV every 24 hours" if the 72-year-old patient weight is 78 kg and has a serum creatinine: 3.2 mg/dL?
Transcribed Image Text:Dose regimen
250 mg/24 h
500 mg/24 h
500 mg/12 h
Creatinine clearance
first dose: 250 mg
first dose: 500 mg
first dose: 500 mg
50 - 20 ml/min
then: 125 mg/24 h
then: 250 mg/24 h
then: 250 mg/12 h
19-10 ml/min
then: 125 mg/48 h
then: 125 mg/24 h
then: 125 mg/12 h
< 10 ml/min (including
haemodialysis and CAPD)
then: 125 mg/48 h
then: 125 mg/24 h
then: 125 mg/24 h
1
1No additional doses are required after haemodialysis or continuous ambulatory peritoneal dialysis (CAPD).
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