“Tris” is short for tris(hydroxymethyl)aminomethane.This weak base is widely used in biochemical research forthe preparation of buffers. It offers low toxicity and a pKb(5.92 at 25°C) that is convenient for the control of pHin clinical applications. A buffer is prepared by mixing0.050 mol of tris with 0.025 mol of HCl in a volume of2.00 L. Compute the pH of the solution.

Principles of Modern Chemistry
8th Edition
ISBN:9781305079113
Author:David W. Oxtoby, H. Pat Gillis, Laurie J. Butler
Publisher:David W. Oxtoby, H. Pat Gillis, Laurie J. Butler
Chapter15: Acid–base Equilibria
Section: Chapter Questions
Problem 43P
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“Tris” is short for tris(hydroxymethyl)aminomethane.
This weak base is widely used in biochemical research for
the preparation of buffers. It offers low toxicity and a pKb
(5.92 at 25°C) that is convenient for the control of pH
in clinical applications. A buffer is prepared by mixing
0.050 mol of tris with 0.025 mol of HCl in a volume of
2.00 L. Compute the pH of the solution.

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