Traits are inherited germ line wise (vertical inheritance) and somatic (epigenetics) inheritance, what exactly is the difference in the traits manifestation between the two indicated inheritances?
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Traits are inherited germ line wise (vertical inheritance) and somatic (epigenetics) inheritance, what exactly is the difference in the traits manifestation between the two indicated inheritances?
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- Regarding Mendelian inheritance in diploid individuals, (Read each statement carefully. Select all of the statements below that are true (that you agree with). Leave any statements that are false (that you do not agree with) un- selected.) a diploid individual receives two copies of every autosome from the previous generation. for every autosomal gene inherited by an individual, both copies can come from one parent. a diploid individual gives two copies of every autosome to a child in the next generation. to be diploid means that two independent genes are specified in the individual's genotype.Familial retinoblastoma, a rare autosomal dominant defect, arose in a large family that had no prior history of the disease. Consider the following pedigree (the darkly colored symbols represent affected individuals): a. Circle the individual(s) in which the mutation most likely occurred. b. Is the person who is the source of the mutation affected by retinoblastoma? Justify your answer. c. Assuming that the mutant allele is fully penetrant, what is the chance that an affected individual will have an affected child?The gene controlling ABO blood type and the gene underlying nail-patella syndrome are said to show linkage. What does that mean in terms of their relative locations in the genome? What does it mean in terms of how the two traits are inherited with respect to each other?
- The following genotypes of two independently assorting autosomal genes determine coat color in rats:A-B- (gray); A-bb (yellow); aaB-(black); aabb (cream)A third gene pair on a separate autosome determines whetherany color will be produced. The CC and Cc genotypes allow coloraccording to the expression of the A and B alleles. However,the cc genotype results in albino rats regardless of the A and Balleles present. Determine the F1 phenotypic ratio of the followingcrosses: (a)AAbbCC * aaBBcc; (b) AaBBcc * AABbcc;(c) AaBbCc * AaBbcc.Lamarck is remembered for his theory of inheritance which hypothesized that physical characteristics acquired during an individuals lifetime were passed onto their offspring (long neck in giraffes). How does this differ from epigenetic inheritance where the diet of the agouti/diabetic mother affects coat color and body size of the offspring (born brown and slim)? O The change in coat color occurs in the offspring and not in the mother O Diet has no impact on fur color, but it can effect body size O There is no difference between Lamarckian theories of inhertiance and epigenetic inheritance O Many genes are involved in determining fur color and body size, making it unlikely that DNA methylation can cause a persistent change in fur color and body sizeThe following pedigree illustrates the inheritance of a rare neurologicaldisease. What is the most likely mode of inheritance for this disorder?Explain your reasoning.
- Explain in your own words why the terms "dominant" and "recessive" in terms of genetic inheritance are context dependant. Typically, the terms dominant and recessive refer to the phenotype and not to alleles. In your answer, also explain why this is the case. If all cells carry the same DNA information, how is it that different cells may carry out different functions or that particular traits be expressed at different times of an organism's lifetime?Individuals, such as Ryan Clark and Geno Atkins, heterozygous for the sickle cell allele show effects of the allele under some circumstances (refer to the linked article and Mendelian patterns of inheritance in your text). Explain in terms of gene expression. http://www.nfl.com/news/story/0ap3000000714754/article/coleman-unsure-on-denver-game-due-to-sickle-cell-traitExplain at the biochemical or enzymatic level, the phenotypic consequencesof alleles incase of following cross. Rr (pink flower) x Rr (pink flower) (progeny are 1 RR (red flower) :2 Rr (pink flower): 1rr(white flower) how alleles contribute to a phenotype through metabolism.
- A complex biochemical pathway is shown below, along with the alleles that either promote or inhibit each step of the pathway leading to a phenotype. Gene A has alleles A and a, B has alleles B and b, and so forth. Genes B and C are duplicate dominant epistatic lethal as heterozygotes (i.e. Bb Cc are lethal). Genes D and E are duplicate dominant epistatic (i.e. dd eg = desired phenotype). If I were to cross AA Bb cc Dd Ee with aa BB Cc Dd e, (i) (ii) What proportion of all offspring don't show the phenotype? What proportion of offspring survive? Gene A Gene B B Gene D a Gene C Gene EProvide a proof that a different phenotype can be produced from the same genotype. What are the possible causes for this different expression? How can the different gene interactions be differentiated from each other and from the Mendelian inheritance?In the following pedigree, is the disorder’s mode of inheritanceautosomal dominant, autosomal recessive, or X-linked recessive?Explain your reasoning.