The structure shown below is of Pitolisant (Waxix®), is a drug to treat narcolepsy. N. Pitolisant – Waxix® Below, see the synthesis of the compound. What are the reactions used? OMs CI. OH OH O Two Williamson ether synthesis reactions. O Aminal formation followed by an ether interchange reaction. O An SN2 reaction followed by a Williamson synthesis.

Organic Chemistry
9th Edition
ISBN:9781305080485
Author:John E. McMurry
Publisher:John E. McMurry
Chapter22: Carbonyl Alpha-substitution Reactions
Section22.SE: Something Extra
Problem 64AP: The key step in a reported laboratory synthesis of sativene, a hydrocarbon isolated from the mold...
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The structure shown below is of Pitolisant (Waxix®), is a drug to treat narcolepsy.
CI
Pitolisant – Waxix®
Below, see the synthesis of the compound. What are the reactions used?
OMs
OH
OH
CI
CI
O Two Williamson ether synthesis reactions.
O Aminal formation followed by an ether interchange reaction.
O An SN2 reaction followed by a Williamson synthesis.
Transcribed Image Text:The structure shown below is of Pitolisant (Waxix®), is a drug to treat narcolepsy. CI Pitolisant – Waxix® Below, see the synthesis of the compound. What are the reactions used? OMs OH OH CI CI O Two Williamson ether synthesis reactions. O Aminal formation followed by an ether interchange reaction. O An SN2 reaction followed by a Williamson synthesis.
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