The normal pH of blood is 7.40 ± 0.05 and is controlled in part by a H2CO3/HCO3 2 buffer system.(a) Assuming that the Ka value for carbonic acid at 25°C applies toblood, what is the [H2CO3]/[HCO3-] ratio in normal blood?(b) In a condition called acidosis, the blood is too acidic. What isthe [H2CO3]/[HCO3-] ratio in a patient whose blood pH is 7.20?

Organic Chemistry
9th Edition
ISBN:9781305080485
Author:John E. McMurry
Publisher:John E. McMurry
Chapter20: Carboxylic Acids And Nitriles
Section20.3: Biological Acids And The Henderson–hasselbalch Equation
Problem 5P: Calculate the percentages of dissociated and undissociated forms present in the following solutions:...
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The normal pH of blood is 7.40 ± 0.05 and is controlled in part by a H2CO3/HCO3 2 buffer system.
(a) Assuming that the Ka value for carbonic acid at 25°C applies to
blood, what is the [H2CO3]/[HCO3-] ratio in normal blood?
(b) In a condition called acidosis, the blood is too acidic. What is
the [H2CO3]/[HCO3-] ratio in a patient whose blood pH is 7.20?

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