The Michaelis-Menten equation models the hyperbolic relationship between [S] and the initial reaction rate Vo for an enzyme-catalyzed, single-substrate reaction E + SES →→E + P. The model can be more readily understood when comparing three conditions: [S] << Km, [S] = Km, and [S] >> Km. Match each statement with the condition that it describes. Note that "rate" refers to initial velocity Vo where steady state conditions are assumed. [Etotal] refers to the total enzyme concentration and [Efree] refers to the concentration of free enzyme. [S] << Km Almost all active sites are empty. The rate is half of the maximum rate. [S] = Km Answer Bank Increasing [Etotal] will increase Km. [S] >> Km [ES] is much higher than [Efree). This condition rarely occurs for most in vivo enzymes. Not true for any of these conditions The rate is directly proportional to [S].

The Michaelis-Menten equation models the hyperbolic relationship between [S] and the initial reaction rate Vo for an enzyme-catalyzed, single-substrate reaction E + SES →→E + P. The model can be more readily understood when comparing three conditions: [S] << Km, [S] = Km, and [S] >> Km. Match each statement with the condition that it describes. Note that "rate" refers to initial velocity Vo where steady state conditions are assumed. [Etotal] refers to the total enzyme concentration and [Efree] refers to the concentration of free enzyme. [S] << Km Almost all active sites are empty. The rate is half of the maximum rate. [S] = Km Answer Bank Increasing [Etotal] will increase Km. [S] >> Km [ES] is much higher than [Efree). This condition rarely occurs for most in vivo enzymes. Not true for any of these conditions The rate is directly proportional to [S].

Chemistry: The Molecular Science

5th Edition

ISBN:9781285199047

Author:John W. Moore, Conrad L. Stanitski

Publisher:John W. Moore, Conrad L. Stanitski

Chapter11: Chemical Kinetics: Rates Of Reactions

Section: Chapter Questions

Problem 83QRT

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