The following sequence of DNA is part of the normal, wild-type gene.   5'TAC CGG GAC TTG AGC CGA TAG 3'   A deletion occurs during DNA replication, causing the guanine shown in red to be removed from the nucleotide strand. What effect is this most likely to have on the final protein?   Multiple Choice   The deletion of the G will cause a single amino acid substitution in the codon in which it occurs.   The deletion of the G will cause a frameshift, so that the first amino acid after the mutation will change but

Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN:9781305251052
Author:Michael Cummings
Publisher:Michael Cummings
Chapter9: Gene Expression And Gene Regulation
Section: Chapter Questions
Problem 16QP: Given the following tRNA anticodon sequence, derive the mRNA and the DNA template strand. Also,...
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The following sequence of DNA is part of the normal, wild-type gene.

 

5'TAC CGG GAC TTG AGC CGA TAG 3'

 

A deletion occurs during DNA replication, causing the guanine shown in red to be removed from the nucleotide strand. What effect is this most likely to have on the final protein?

 

Multiple Choice
  •  

    The deletion of the G will cause a single amino acid substitution in the codon in which it occurs.

  •  

    The deletion of the G will cause a frameshift, so that the first amino acid after the mutation will change but the rest of the protein is unaffected.

  •  

    The deletion of the G will cause a frameshift, resulting in a premature stop codon and a truncated protein.

  •  

    The deletion of the G will cause a frameshift, resulting in the loss of the normal stop codon and an abnormally long protein with an altered amino acid sequence.

  •  

    The deletion of the G will not have an effect on the final protein.

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