TABLE 9–27 Exposure to Lead Paint and ADHD by Father’s Diagnosis Father with ADHD Exposure to Lead Paint ADHD No ADHD Yes 27 39 No 7 37 1. Use the data in Problem 2 to estimate the relative risk and odds ratio for a child’s diagnosis of ADHD relative to exposure to lead paint, adjusted for the father’s diagnosis using the Cochran–Mantel–Haenszel method. 6. A study is conducted in patients with HIV. The primary outcome is CD4 cell count, which is a measure of the stage of the disease. Lower CD4 counts are associated with more advanced disease. The investigators are interested in the association between vitamin and mineral supplements and CD4 count. A multiple regression analysis is performed relating CD4 count to the use of supplements (coded as 1 = yes and 0 = no) and to the duration of HIV in years (i.e., the number of years between the diagnosis of HIV and the study date). For the analysis, y = CD4 count: 1. If we compare two patients and one has had HIV for 5 years longer than the other, what is the expected difference in their CD4 counts?

Calculus For The Life Sciences
2nd Edition
ISBN:9780321964038
Author:GREENWELL, Raymond N., RITCHEY, Nathan P., Lial, Margaret L.
Publisher:GREENWELL, Raymond N., RITCHEY, Nathan P., Lial, Margaret L.
Chapter10: Matrices
Section10.EA: Extended Application Contagion
Problem 2EA
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TABLE 9–27 Exposure to Lead Paint and ADHD by Father’s Diagnosis

Father with ADHD

Exposure to Lead Paint

ADHD

No ADHD

Yes

27

39

No

7

37

1. Use the data in Problem 2 to estimate the relative risk and odds ratio for a child’s diagnosis of ADHD relative to exposure to lead paint, adjusted for the father’s diagnosis using the Cochran–Mantel–Haenszel method.

6. A study is conducted in patients with HIV. The primary outcome is CD4 cell count, which is a measure of the stage of the disease. Lower CD4 counts are associated with more advanced disease. The investigators are interested in the association between vitamin and mineral supplements and CD4 count. A multiple regression analysis is performed relating CD4 count to the use of supplements (coded as 1 = yes and 0 = no) and to the duration of HIV in years (i.e., the number of years between the diagnosis of HIV and the study date). For the analysis, y = CD4 count:

1. If we compare two patients and one has had HIV for 5 years longer than the other, what is the expected difference in their CD4 counts?

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