Significant change to the native way of life was largely unintentional. One of these unintentional effects was the rapid spread of new, and deadly diseases that decimated the native populations. True/false 2. The ——————not only facilitated trade between the Old World and the New World, but significantly changed the social and ecological systems of both. 3. What other major social, political or economic change stood out to you and why?

Significant change to the native way of life was largely unintentional. One of these unintentional effects was the rapid spread of new, and deadly diseases that decimated the native populations. True/false 2. The ——————not only facilitated trade between the Old World and the New World, but significantly changed the social and ecological systems of both. 3. What other major social, political or economic change stood out to you and why?