reaction with HCI reaction with PBR3 followed by NaCI reaction with tosyl chloride, followed by hydroxide reaction with Kl followed by NaCl reaction with SOCI2
reaction with HCI reaction with PBR3 followed by NaCI reaction with tosyl chloride, followed by hydroxide reaction with Kl followed by NaCl reaction with SOCI2
Organic Chemistry
8th Edition
ISBN:9781305580350
Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Chapter17: Carboxylic Acids
Section: Chapter Questions
Problem 17.29P
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Chiral alcohols can be converted to chlorides by several pathways. Which is the best way to make the chloride with retention of configuration?
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