Propose an efficient synthesis process for this transformation. HO,

Organic Chemistry
9th Edition
ISBN:9781305080485
Author:John E. McMurry
Publisher:John E. McMurry
Chapter22: Carbonyl Alpha-substitution Reactions
Section22.SE: Something Extra
Problem 64AP: The key step in a reported laboratory synthesis of sativene, a hydrocarbon isolated from the mold...
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organic chemistry 

please solve the following 

 

Xor
Propose an efficient synthesis process for this transformation.
HO
Transcribed Image Text:Xor Propose an efficient synthesis process for this transformation. HO
Expert Solution
Step 1

Williamson Ether Synthesis:

Williamson ether synthesis is a type of coupling reaction for the formation of ethers. This reaction involves the formation of an ether from an alkyl halide and an alcohol. 

The reaction involves SNmechanism for the attack of the alkoxide ion on the alkyl halide.

 

R-O-  + R'-X    R-O-R' + X-where,R-O- is the alkoxide ionR'-X is the alkyl halideR-O-R' is the Ether

Step 2

The given reactant is-

Chemistry homework question answer, step 2, image 1

 

Step 1 : Formation of the alkoxide ion from the given alcohol by using sodium

 

Chemistry homework question answer, step 2, image 2

 

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