ook at this drug mainly ionized could be mainl he stomach testine 8 Flood 735 side the cell exboxy Ka1= 5 and p ch not

Principles Of Pharmacology Med Assist
6th Edition
ISBN:9781337512442
Author:RICE
Publisher:RICE
Chapter8: Forms Of Drugs And How They Act
Section: Chapter Questions
Problem 26RQ
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t=10
+1 = 100
PL
0/0
/+/6 (PKPH)
2- Intestine 8
3- Blood 7.35
4- Inside the cell L
carboxy
160
1410(PH-PKG)
تانت
مجموعة
الكروكمل
Z
Look at this drug carefully, and determine where it would
be mainly ionized??
it would be mainly ionized in:
1- The stomach 2
100
1410(5-2)
S
= 99.99% lonized
M
Assignment
راح تتأتب
و مجموعة الأمين
If pka1= 5 and pKa2=10 which group will ionize
which not
20 Amin
вка
PR.-log
3
agog ionized
99 190 unionized
HO
HO
Coal
N
H₂C
carday!
Multiple functional
20 mr
min
N
H
150
group
CH3
42
Transcribed Image Text:t=10 +1 = 100 PL 0/0 /+/6 (PKPH) 2- Intestine 8 3- Blood 7.35 4- Inside the cell L carboxy 160 1410(PH-PKG) تانت مجموعة الكروكمل Z Look at this drug carefully, and determine where it would be mainly ionized?? it would be mainly ionized in: 1- The stomach 2 100 1410(5-2) S = 99.99% lonized M Assignment راح تتأتب و مجموعة الأمين If pka1= 5 and pKa2=10 which group will ionize which not 20 Amin вка PR.-log 3 agog ionized 99 190 unionized HO HO Coal N H₂C carday! Multiple functional 20 mr min N H 150 group CH3 42
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