Question 5: Phenylketonuria (PKU) is a rare, mendelian, recessive geneticdisorder where individuals lack the enzyme phenylalanine hydroxylase, which isnecessary for conversion of the amino acid phenylalanine to tyrosine. Inindividuals with PKU, phenylalanine builds up in the circulatory system to levelsthat are toxic. Assuming that the population is in equilibrium, if 1 in 10,000individuals have PKU, what proportion of the population is a carrier (i.e., isheterozygous) for the PKU allele? Question 1. Is the population in H-W equilibrium?Observed genotype frequencies●■●f[A₁A₁] =0.16f[A₁A₂] =0.48f[A₂A₂] =0.36O Question 2. Is the population in H-W equilibrium?Observed genotype frequenciesf[A₁A₁] =0.04f[A₁A₂] =0.12● f[A₂A₂] =0.84●Question 3. Is the population in H-W equilibrium?Observed genotype numbersA₁A₁ =40A1A2 =20● A₂A2 =40O Question 4: Is the population in H-W equilibrium?Observed number of each genotypeA1A1=36●● A1A2=28A2A2=36Note that raw numbers are given. The question is whether observedfrequencies = expected frequencies. You must first compute thegenotype frequencies.

Name: Question 5: Phenylketonuria (PKU) is a rare, mendelian, recessive gen
Uploaded: 2024-03-20T06:42:55.000Z
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Description: Question 5: Phenylketonuria (PKU) is a rare, mendelian, recessive geneticdisorder where individuals lack the enzyme phenylalanine hydroxylase, which isnecessary for conversion of the amino acid phenylalanine to tyrosine. Inindividuals with PKU, phen