NH2 H2SO4 CH, —СН—СН, 1. CH,=CH-CH=0 2. -NO2 ОН 2 H,O glycerol НО НО quinoline

Chemistry
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Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
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Chapter1: Chemical Foundations
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Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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Quinolines, heterocyclic compounds that contain a pyridine ring fused to a benzene ring, are commonly synthesized by a method known as the Skraup
synthesis, in which aniline reacts with glycerol under acidic conditions. Nitrobenzene is added to the reaction mixture to serve as an oxidizing agent.
The first step in the synthesis is the dehydration of glycerol to propenal.

a. What product would be obtained if para-ethylaniline were used instead of aniline?
b. What product would be obtained if 3-hexen-2-one were used instead of glycerol?
c. What starting materials are needed for the synthesis of 2,7-diethyl-3-methylquinoline?

NH2
H2SO4
CH, —СН—СН,
1.
CH,=CH-CH=0
2.
-NO2
ОН
2 H,O
glycerol
НО НО
quinoline
Transcribed Image Text:NH2 H2SO4 CH, —СН—СН, 1. CH,=CH-CH=0 2. -NO2 ОН 2 H,O glycerol НО НО quinoline
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