Malonic ester synthesis 4. Write the reaction showing all intermediates when H₂C(CO₂Et)2 (diethyl malonate) is reacted with NaOEt followed by 1) ethyl iodide; 2) NaOH; 3) H3O*; 4) A. Hint: Remember that B-oxo carboxylic undergo decarboxylation (loss of 1 equivalent of CO₂) when strongly heated. acids

Malonic ester synthesis 4. Write the reaction showing all intermediates when H₂C(CO₂Et)2 (diethyl malonate) is reacted with NaOEt followed by 1) ethyl iodide; 2) NaOH; 3) H3O*; 4) A. Hint: Remember that B-oxo carboxylic undergo decarboxylation (loss of 1 equivalent of CO₂) when strongly heated. acids

Organic Chemistry

8th Edition

ISBN:9781305580350

Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Chapter20: Dienes, Conjugated Systems, And Pericyclic Reactions

Section: Chapter Questions

Problem 20.27P

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