lecall your study of equilibria and kinetics from general chemistry. You used equations with upper case Cand iower case k during the study of equilibria and kinetics respectively. What do the upper and lower ase letters refer to?

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Chapter5: The X-ray Tube
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. Recall your study of equilibria and kinetics from general chemistry. You used equations with upper case
Kand lower case k during the study of equilibria and kinetics respectively. What do the upper and lower
case letters refer to?
Transcribed Image Text:. Recall your study of equilibria and kinetics from general chemistry. You used equations with upper case Kand lower case k during the study of equilibria and kinetics respectively. What do the upper and lower case letters refer to?
affinity of enzymes for substrate. Explain why this approximation makes sense. Does a large KM in
4,5
Graph 1
3.5
3.
Km
V, V LST V
2.5
Equatilon 1
1.5
0.5
Equation 2 E+S ES E+P
0.
10
[S). mM
15
Equation 3 K th,
to
[S), and number of substrates per reaction. Generate a finalized list of assumptione
3. Define the term Var in your own words
max
4. Solve the Michaelis-Menten equation for KM when o = Vmax /2. What does this tell you about the
relationship between (substrate] and enzymes with high KM values? With low KM values? Makea
generalization.
%3D
5. a. What is the Ky value as you can estimate it from Graph 1?
b. On Graph 1, draw a curve that has the same V, but a smaller KM value.
3. Examine Equation 2. When k, is very small compared to k the KM
max
high or low affinity of enzyme for substrate?
becomes an approximation o
indicate
Velocity, mM product/ min
Transcribed Image Text:affinity of enzymes for substrate. Explain why this approximation makes sense. Does a large KM in 4,5 Graph 1 3.5 3. Km V, V LST V 2.5 Equatilon 1 1.5 0.5 Equation 2 E+S ES E+P 0. 10 [S). mM 15 Equation 3 K th, to [S), and number of substrates per reaction. Generate a finalized list of assumptione 3. Define the term Var in your own words max 4. Solve the Michaelis-Menten equation for KM when o = Vmax /2. What does this tell you about the relationship between (substrate] and enzymes with high KM values? With low KM values? Makea generalization. %3D 5. a. What is the Ky value as you can estimate it from Graph 1? b. On Graph 1, draw a curve that has the same V, but a smaller KM value. 3. Examine Equation 2. When k, is very small compared to k the KM max high or low affinity of enzyme for substrate? becomes an approximation o indicate Velocity, mM product/ min
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