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Discuss and illustrate comprehensively using the I - and M - effect
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- noradrenaline and serotonin in the spinal cord. Deduce the structure of this new compound, given its molecular neuron to another. Noradrenaline (also called norepinephrine) and serotonin are neurotransmitters that act in its) Neurotransmitters are small molecules that are produced by the body to send messages from one the central nervous system. A recently report synthetic compound has effects that are similar to baul formula (CəH13NO) and the following 'H NMR spectral data. Show your work by labeling your proposed structure with the corresponding letters for the signals listed below. a) 1.1 6 (2H, broad singlet) b) 2.7 6 (2H, triplet) c) 2.9 6 (2H, triplet) d) 3.8 6 (3H, singlet) e) 6.8 6 (2H, doublet) f) 7.1 6 (2H, doublet)How Tightly Do Transition-State Analogs Bind to the ActiveSite?Know classification/mechanism of inhibition for: phenolics, halogens, oxidizers, heavy metals, surfactants (quaternary ammonium halide, soaps, detergents), alcohols, alkylating agents. Be able to give an example for each class of chemical.
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- Please help, I keep getting this question wrong- classify the two groups attached to the ring in salicylamide as activators ordeactivators. Then classify the directing effects of the two groups. thanks in advanceReversed phase HPLC refers to the condition of stationary phase and a mobile phase of separation. Select the best condition A. A hydrophilic stationary phase is combined with a non-polar mobile phase. B. A hydrophilic stationary phase is combined with a polar mobile phase C. A hydrophobic stationary phase is combined with a polar mobile phase. D. A hydrophobic stationary phase is combined with a non-polar mobile phase. describe the statementCalculate k, the degradation rate constant, responsible for drug degradation in this solution (in month-1).
- Explain why the solution prepared in part a is a buffer splution. Hint: re read the first page of this experiment:1. Create a flowchart for the synthesis and purification of phenacetin. Draw out your steps for the extraction process and label the organic and aqueous layers in your diagrams. Indicate where the product is in each step. 2. Draw the mechanism for the deprotonation of the phenol group of acetaminophen by potassium carbonate. Label the acid, base, conjugate acid and conjugate base. How do you know potassium carbonate is a strong enough base to do this deprotonation?3. You are given a mixture of aspirin, phenol, and naphthalene that you need to separate. i) Draw the structures of each, and identify if they are acidic, basic, or neutral compounds. For each compound draw their reaction with the appropriate acidic or basic conditions that will change their solubility and allow them to be separated. ii) What modifications would you have to make to the experimental protocol in order to separate these three compounds? Provide specifics.