Intro to Neuro QuestionDopamine input from the substantia nigra to the striatum results in which of the following? increased firing of thalamus neurons decreased firing of thalamus neurons increased firing of globus pallidus internal neurons decreased firing of globus pallidus internal neurons increased firing of globus pallidus external neurons decreased firing of globus pallidus external neuronsGroup of answer choicesI, III and VI, IV and VII, III and VI, IV, and VIIs my reasoning correct? Dopamine from the substantia nigra:Excites the direct pathway in the striatum, leading to decreased activity in the globus pallidus internal (GPi) and increased activity in the thalamus.Inhibits the indirect pathway in the striatum, resulting in decreased activity in the globus pallidus external (GPe) and further decreasing GPi activity, which also increases thalamic activity.So, the effects are:Increased firing of thalamus neurons.Decreased firing of globus pallidus internal neurons.Decreased firing of globus pallidus external neurons.Answer: I, IV, and VI.

Dopamine is a neurotransmitter that plays a key role in motor control, motivation, and reward. It is…

Answered: Intro to Neuro Question Dopamine input…

Human Physiology: From Cells to Systems (MindTap Course List)

9th Edition

ISBN:9781285866932

Author:Lauralee Sherwood

Publisher:Lauralee Sherwood

Chapter6: The Peripheral Nervous System: Afferent Division; Special Senses

Section: Chapter Questions

Problem 13RE

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Intro to Neuro Question

Dopamine input from the substantia nigra to the striatum results in which of the following? increased firing of thalamus neurons decreased firing of thalamus neurons increased firing of globus pallidus internal neurons decreased firing of globus pallidus internal neurons increased firing of globus pallidus external neurons decreased firing of globus pallidus external neurons

Group of answer choices

I, III and V

I, IV and V

II, III and V

I, IV, and VI

Is my reasoning correct? Dopamine from the substantia nigra:

Excites the direct pathway in the striatum, leading to decreased activity in the globus pallidus internal (GPi) and increased activity in the thalamus.
Inhibits the indirect pathway in the striatum, resulting in decreased activity in the globus pallidus external (GPe) and further decreasing GPi activity, which also increases thalamic activity.

So, the effects are:

Increased firing of thalamus neurons.
Decreased firing of globus pallidus internal neurons.
Decreased firing of globus pallidus external neurons.

Answer: I, IV, and VI.

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