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In this part, you will work out on X-linked traits. Remember that males have only one X chromosome and females have two.
For X-linked recessive, use the following designations:
XA= normal
Xa= the trait (a genetic disease or abnormality)
For X-linked dominant, use the following designations:
XA= the trait (a genetic disease or abnormality)
Xa= normal
Determine if the pedigrees below can be for a trait that is X-linked recessive. Write the genotype next to the symbol for each person in the pedigree below.
A. Is it possible that this pedigree is for an X-linked recessive trait?
B. What can you conclude about the children of mothers affected with an X-linked recessive characteristic?
C. What can you conclude about the father of an affected female?
Step by step
Solved in 2 steps
- Redgreen color blindness is an X-linked recessive disorder in humans. Your friend is the daughter of a color-blind father. Her mother had normal color vision, but her maternal grandfather was color-blind. What is the probability that your friend is color-blind? (a) 1 (b) (c) (d) (e) 0There are several possible modes of inheritance through which traits can be inherited. The following pedigree charts represent four different inheritance patterns. Match each type of inheritance with the correct pedigree numbered above. (Use each number only once.)X-linked recessive X-linked dominant Autosomal recessive Autosomal dominantColor blindness is an X-linked recessive disease. A female and a male with normal vision have 4 children. The phenotypes of the children are listed below: 2 Colorblind males, 1 normal vision female, one normal vision male. Given these results, the female must be a carrier for colorblindness. True False
- An individual with 46, XX genotype is diagnosed with Duchenne-type Muscular Dystrophy, a recessive X-linked disorder. Genetic tests confirm that this individual is a heterozygote for this disorder. Briefly, but specifically, explain how it’s possible that they are showing symptoms of this disorder.In humans, the ABO blood type is under the control of autosomal multiple alleles. Color blindness is a recessive X-linked trait. If two parents who are both type A and have normal vision produce a son who is color-blind and is type O, what is the probability that their next child will be a female who has normal vision and is type O?In humans, the ABO blood type is under the control of autosomal multiple alleles. Color blindness is a recessive X-linked trait. If two parents who are both type A and have normal vision produce a son who is color blind and is type O, what is the probability that their next child will be a female who has normal vision and is type O?
- Geneticists are concerned about three different genetic conditions present within their family. Achondroplasia is an autosomal dominant genetic disorder that results in short-limbed dwarfism. (A = achondroplasia allele; a = average height allele). Red-Green Color blindness is an X-linked recessive genetic disorder (Xc = color blindness allele; XC = normal color vision allele). The 7-year-old son has an autosomal recessive form of deafness. (h = deafness allele; H = normal hearing allele.) All three family members were karyotyped, and additional genetic testing was performed to determine the chromosomal location of the genes being studied. The figures below show the karyotypes of the mother and father with respect to the chromosomes containing the three genes mentioned above. Question: The couple’s 7-year-old son has all three of these genetic conditions (achondroplasia, color blindness and deafness). Taking into consideration the genotypes of his parents, what is the complete…X‑linked, recessive diseases, such as hemophilia, are extremely rare in the population. However, many women are carriers and show no sign of the disease. The pedigree illustrates the inheritance of an X‑linked, recessive disease. Determine whether the unknown individuals are affected by the disease, unaffected by the disease, or carriers of the X‑linked recessive allele. Unaffected individuals are not carriers of the X‑linked recessive allele.Hemophilia is another example of a X-linked disease caused when a recessive allele (Xh) is expressed. If a normal male reproduces with a heterozygous normal female, what are the expected genotypes and phenotypes? Will any of their daughters develop hemophilia? you must also give the gender of the child in your genotype and phenotype descriptions here.
- Hemophilia is an X-linked recessive disorder and blood type is autosomal. If two healthy parents, one of which is blood type A and the other blood type B, produce a son who has hemophilia and is type O, what is the probability that their next child will be a son with hemophilia and blood type B? 1/2 3/16 1/4 1/8 1/16A gene that controls the ability to see red and green is located on the X chromosome but not on the Y chromosome. There is a recessive nonfunctional allele for this gene that can cause red-green color blindness if the person possessing it does not also have the dominant normal gene. Consider the case of a carrier mother who is heterozygous for the red-green vision gene and a father who has normal vision. Use XB = normal vision, Xb = color-blind vision. What is the chance the parents would have a color-blind boy? A color-blind girl? What about a girl or boy with normal vision? Redo the Punnett square for a carrier mother (XBXb) and a color-blind father (XbY). Do the chances of having color-blind children change? How?The gene for polydactyly (P) is autosomal and dominant to normal fingers (p). Hemophilia is sex-linked and recessive (X h ). A man and his wife both of whom are polydactylous and have normal red blood cells have a child who is non-polydactylous and with hemophilia. What are their genotypes?