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In skeletal muscle under anaerobic conditions, pyruvate is further reduced to lactate. What is the net equation for the pavoff phase of glycolvsis?

In skeletal muscle under anaerobic conditions, pyruvate is further reduced to lactate. What is the net equation for the pavoff phase of glycolvsis?

Biochemistry
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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Use the following table for all questions in the problem set related to glycolysis: TABLE 18.1 Reactions and Thermodynamics of Glycolysis AG" AG Reaction Enzyme (k/mol) at 25°c (kJ/mol) Hexokinase Glucokinase a-D-Glucose + ATPt-= -16.7 850 -33.9* glucose-6-phosphate?- + ADP- + H* Glucose-6 phosphate²-=fructose-6-phosphate- Fructose-6-phosphate- + ATP-= fructose-1,6-bisphosphate- + ADP- + H* Fructose-1,6-bisphosphate dihydroxyacetone-P- + glyceraldehyde-3-P:- Dihydroxyacetone-P=glyceraldehyde-3-P- Glyceraldehyde-3-P- + P?- + NAD*= 1,3-bisphosphoglycerate- + NADH + H* 1,3-Bisphosphoglycerate + ADP- Phosphoglucoisomerase Phosphofructokinase +1.67 0.51 -2.92 -14.2 310 -18.8 Fructose bisphosphate aldolase +23.9 6.43 X 10-3 -0.23 Triose phosphate isomerase Glyceraldehyde-3-P dehydrogenase Phosphoglycerate kinase +7.56 0.0472 +2.41 +6.30 0.0786 -1.29 -18.9 2060 +0.1 3-Pglycerate- + ATP- 3-Phosphoglycerate =2phosphoglycerate 2-Phosphoglycerate-= Phosphoglycerate mutase +4.4 0.169 +0.83 Enolase +1.8 0.483 +1.1 phosphoenolpyruvate-+ H,0 Phosphoenolpyruvate- + ADP- + H* = Pyruvate + ATpt- Pyruvate + NADH + H*= lactate" + NAD* Pyruvate kinase -31.7 3.63 x 10 -23.0 Lactate dehydrogenase -25.2 2.63 x 10 -14.8
Transcribed Image Text:Use the following table for all questions in the problem set related to glycolysis: TABLE 18.1 Reactions and Thermodynamics of Glycolysis AG" AG Reaction Enzyme (k/mol) at 25°c (kJ/mol) Hexokinase Glucokinase a-D-Glucose + ATPt-= -16.7 850 -33.9* glucose-6-phosphate?- + ADP- + H* Glucose-6 phosphate²-=fructose-6-phosphate- Fructose-6-phosphate- + ATP-= fructose-1,6-bisphosphate- + ADP- + H* Fructose-1,6-bisphosphate dihydroxyacetone-P- + glyceraldehyde-3-P:- Dihydroxyacetone-P=glyceraldehyde-3-P- Glyceraldehyde-3-P- + P?- + NAD*= 1,3-bisphosphoglycerate- + NADH + H* 1,3-Bisphosphoglycerate + ADP- Phosphoglucoisomerase Phosphofructokinase +1.67 0.51 -2.92 -14.2 310 -18.8 Fructose bisphosphate aldolase +23.9 6.43 X 10-3 -0.23 Triose phosphate isomerase Glyceraldehyde-3-P dehydrogenase Phosphoglycerate kinase +7.56 0.0472 +2.41 +6.30 0.0786 -1.29 -18.9 2060 +0.1 3-Pglycerate- + ATP- 3-Phosphoglycerate =2phosphoglycerate 2-Phosphoglycerate-= Phosphoglycerate mutase +4.4 0.169 +0.83 Enolase +1.8 0.483 +1.1 phosphoenolpyruvate-+ H,0 Phosphoenolpyruvate- + ADP- + H* = Pyruvate + ATpt- Pyruvate + NADH + H*= lactate" + NAD* Pyruvate kinase -31.7 3.63 x 10 -23.0 Lactate dehydrogenase -25.2 2.63 x 10 -14.8
In skeletal muscle under anaerobic conditions, pyruvate is further reduced to lactate. What is the net equation for the payoff phase of glycolysis? O glyceraldehyde-3-phosphate + 2 ATP + Pi ---> lactone + NAD+ glucose+2ATP ---> 2Glyceraldehyde-3-Phosphate + 2ADP + 2H+ 2glyceraldehyde-3-phosphate + 4ADP + 2Pi >2Lactate + 4ATP O None of the above
Transcribed Image Text:In skeletal muscle under anaerobic conditions, pyruvate is further reduced to lactate. What is the net equation for the payoff phase of glycolysis? O glyceraldehyde-3-phosphate + 2 ATP + Pi ---> lactone + NAD+ glucose+2ATP ---> 2Glyceraldehyde-3-Phosphate + 2ADP + 2H+ 2glyceraldehyde-3-phosphate + 4ADP + 2Pi >2Lactate + 4ATP O None of the above
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