In mice, the wild-type coat color, agouti (AA) [left mouse], is dominant to solid-colored, black fur (aa) [middle mouse]. However, a separate gene (C) is necessary for pigment production. A mouse that is homozygous for a recessive c allele at this locus is unable to produce pigment and is albino [right mouse] regardless of the allele present at locus A. Thus, the following genotypes are listed with their associated phenotypes: ~ A/A; C/C or A/A; C/c or A/a; C/C or A/a; C/c ==> "agouti" ~ a/a; C/C or a/a; C/c ==> "black" ~ A/A; c/c or A/a; c/c or a/a; c/c or a/a; c/c ==> "albino" This is an example of recessive epistasis, in which the recessive c allele "stands upon" the possible genotypes for the A gene (A/A, A/a, or a/a). If two agouti mice with the A/a; C/c genotype are mated, what is the expected phenotypic ratio in their offspring? A.9 albino, 4 agouti, 3 black B. 9 agouti, 4 albino, 3 black C.9 black, 4 albino, 3 agouti D.9 agouti, 4 black, 3 albino
In mice, the wild-type coat color, agouti (AA) [left mouse], is dominant to solid-colored, black fur (aa) [middle mouse]. However, a separate gene (C) is necessary for pigment production. A mouse that is homozygous for a recessive c allele at this locus is unable to produce pigment and is albino [right mouse] regardless of the allele present at locus A. Thus, the following genotypes are listed with their associated phenotypes:
~ A/A; C/C or A/A; C/c or A/a; C/C or A/a; C/c ==> "agouti"
~ a/a; C/C or a/a; C/c ==> "black"
~ A/A; c/c or A/a; c/c or a/a; c/c or a/a; c/c ==> "albino"
This is an example of recessive epistasis, in which the recessive c allele "stands upon" the possible genotypes for the A gene (A/A, A/a, or a/a).
If two agouti mice with the A/a; C/c genotype are mated, what is the expected
A.9 albino, 4 agouti, 3 black
B. 9 agouti, 4 albino, 3 black
C.9 black, 4 albino, 3 agouti
D.9 agouti, 4 black, 3 albino
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