In Gillaspera, what is the general purpose of conversion of glucose to citrate besides of course the generation of citrate and what is the name for this process?  Why is this process generally important in organisms? Give the net reaction for this process in Gillaspera from 1 molecule of glucose to 1 molecule of citrate.  It might help to outline the different steps happening in each compartment.

Biochemistry
6th Edition
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Reginald H. Garrett, Charles M. Grisham
Chapter18: Glycolysis
Section: Chapter Questions
Problem 9P: Comparing Glycolysis Entry Points for Sucrose Sucrose can enter glycolysis by either of two routes:...
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In Gillaspera, what is the general purpose of conversion of glucose to citrate besides of course the generation of citrate and what is the name for this process?  Why is this process generally important in organisms? Give the net reaction for this process in Gillaspera from 1 molecule of glucose to 1 molecule of citrate.  It might help to outline the different steps happening in each compartment.  

Glucose
Citrate
Culture
medium
Glucose
Cytoplasm
Inhibition of
Pyruvate
Pyruvate
carboxylase
Pyruvate
citrate lyase
results in
Acetyl-CoA
\ Citrate
lyase
increased
citrate export
Oxaloacetate
NADH + H*
Oxaloacetate
Cytosolic malate
dehydrogenase
NAD*
Malate
Pyruvate
Pyruvate
dehydrogenase
+ H*
Malate
NAD
NADH
Mitochondrial
malate
dehydrogenase NADH + H*
- NAD*
Acetyl-CoA
Citrate
synthase
Oxaloacetate
Citrate
Citrate
Mitochondrial
matrix
Citrate cycle is partially inhibited
by culture conditions
Transcribed Image Text:Glucose Citrate Culture medium Glucose Cytoplasm Inhibition of Pyruvate Pyruvate carboxylase Pyruvate citrate lyase results in Acetyl-CoA \ Citrate lyase increased citrate export Oxaloacetate NADH + H* Oxaloacetate Cytosolic malate dehydrogenase NAD* Malate Pyruvate Pyruvate dehydrogenase + H* Malate NAD NADH Mitochondrial malate dehydrogenase NADH + H* - NAD* Acetyl-CoA Citrate synthase Oxaloacetate Citrate Citrate Mitochondrial matrix Citrate cycle is partially inhibited by culture conditions
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